Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 7/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | FCER2 | P06734 | 1/20 | 0.41 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 2/20 | 0.40 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.40 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6687785 | 1.00 | CCR1 (0.56) | CCR1TDP1EPHX1MMP1FCER2 | |
| SCHEMBL2675154 | 1.00 | CCR1 (0.56) | CCR1TDP1EPHX1MMP1FCER2 | |
| SCHEMBL7586283 | 1.00 | CCR1 (0.56) | CCR1TDP1EPHX1MMP1FCER2 | |
| SCHEMBL27586171 | 1.00 | CCR1 (0.56) | CCR1TDP1EPHX1MMP1FCER2 | |
| SCHEMBL4068618 | 0.99 | CCR1 (0.55) | CCR1TDP1EPHX1MMP1FCER2 | |
| SCHEMBL4072849 | 0.88 | CCR1 (0.57) | CCR1EPHX1SLC15A1ANPEPCSNK1E | |
| SCHEMBL4061506 | 0.88 | LMNA (0.46) | CCR1TDP1EPHX1SLC15A1ANPEP | |
| SCHEMBL4065521 | 0.85 | CCR1 (0.58) | CCR1EPHX1SLC15A1ANPEPCSNK1E | |
| SCHEMBL4066052 | 0.85 | CCR1 (0.42) | CCR1EPHX1SLC15A1ANPEPCSNK1E | |
| SCHEMBL4065263 | 0.82 | CCR1 (0.46) | CCR1EPHX1SLC15A1ANPEPCSNK1E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0966443-B1 | HETEROARYL-HEXANOIC ACID AMIDE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS SELECTIVE INHIBITORS OF MIP-1-ALPHA BINDING TO ITS CCR1 RECEPTOR | PFIZER (US) | 2009-01-28 | — | — | EP | disclosed |