Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3579316 | 0.92 | SSTR4 (0.41) | SSTR4SLC6A2SLC6A4SLC6A3MAPT | |
| SCHEMBL3576110 | 0.92 | CCR5 (0.38) | SSTR4SLC6A2SLC6A3KCNH2 | |
| SCHEMBL4094876 | 0.91 | SSTR4 (0.44) | SSTR4CYP2D6 | |
| SCHEMBL4093834 | 0.91 | SSTR4 (0.44) | SSTR4CYP2D6 | |
| SCHEMBL4106036 | 0.91 | SSTR4 (0.44) | SSTR4CYP2D6 | |
| SCHEMBL4094874 | 0.91 | SSTR4 (0.44) | SSTR4CYP2D6 | |
| SCHEMBL1096262 | 0.88 | REN (0.37) | SSTR4SLC6A2SLC6A4SLC6A3MAPT | |
| SCHEMBL3576277 | 0.88 | SSTR4 (0.38) | SSTR4SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL3570815 | 0.84 | RPS6KB1 (0.38) | SSTR4SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL4110232 | 0.84 | SSTR4 (0.44) | SSTR4SLC6A2SLC6A4SLC6A3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2085383-A1 | PIPERIDINE DERIVATIVES OR SALTS THEREOF | Astellas Pharma Inc. (JP) | 2009-08-05 | — | — | EP | disclosed |