SCHEMBL4067779

SCHEMBL4067779

Oc1cccc(CCCCF)c1O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IAPP P10997 4/20 0.50
ADAMTS4 O75173 1/20 0.42
ALDH1A1 P00352 1/20 0.42
EGFR P00533 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
LMNA P02545 1/20 0.42
FYN P06241 1/20 0.42
MMP2 P08253 1/20 0.42
MMP9 P14780 1/20 0.42
HPGD P15428 1/20 0.42
ALOX15 P16050 1/20 0.42
MMP8 P22894 1/20 0.42
CA6 P23280 1/20 0.42
CDK2 P24941 1/20 0.42
MMP12 P39900 1/20 0.42
RECQL P46063 1/20 0.42
HSD17B10 Q99714 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
ADAMTS5 Q9UNA0 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10414030 0.89 IAPP (0.59) IAPPADAMTS4ALDH1A1EGFRCA1
SCHEMBL2655419 0.83 TAAR1 (0.59) CA2HSD17B10MGLLTAAR1
SCHEMBL633288 0.82 TAAR1 (0.52) IAPPADAMTS4ALDH1A1EGFRCA1
SCHEMBL15437937 0.82 MGLL (0.61) CA2HSD17B10MGLLTAAR1BID
SCHEMBL7110446 0.82 MGLL (0.61) CA2HSD17B10MGLLTAAR1BID
SCHEMBL8011584 0.81 TYR (0.42) MMP2ALOX15HSD17B10MGLLALOX5
SCHEMBL30431110 0.80 IAPP (0.65) IAPPMMP2ALOX15HSD17B10ALOX5
SCHEMBL9863325 0.80 IAPP (0.50) IAPPBIDBCL2L1MCL1BAK1
SCHEMBL70878 0.80 IAPP (0.65) IAPPMMP2ALOX15HSD17B10ALOX5
SCHEMBL9863155 0.80 IAPP (0.50) IAPPBIDBCL2L1MCL1BAK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3947312-A1 COMPOSITE PRODUCTS AND THE MANUFACTURE THEREOF NewSouth Innovations Pty Limited (AU) 2022-02-09 EP disclosed
EP-3325136-A1 RADIATION-CURABLE COMPOSITIONS, MEMBRANES AND THE MANUFACTURE AND USE OF SUCH MEMBRANES Fujifilm Manufacturing Europe BV (NL) 2018-05-30 EP disclosed
EP-2038327-A2 SILOXANYL MATERIALS FOR MOLDED PLASTICS Johnson & Johnson Vision Care, Inc. (US) 2009-03-25 EP disclosed
WO-2008005398-A2 SILOXANYL MATERIALS FOR MOLDED PLASTICS JOHNSON & JOHNSON VISION CARS, INC. (US) 2008-01-10 WO disclosed
WO-2005003183-A1 ZERO VALENT METAL INITIATED GAS-PHASE DEPOSITION POLYMERIZATION (GDP) HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2005-01-13 WO disclosed