Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 6/20 | 0.64 |
| ▸ | MAPT | P10636 | 6/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.64 |
| ▸ | PKM | P14618 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | CLK1 | P49759 | 1/20 | 0.54 |
| ▸ | GSK3B | P49841 | 1/20 | 0.54 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.54 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.54 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4063361 | 0.89 | ALDH1A1 (0.64) | HTTMAPTLMNAPKMALDH1A1 | |
| SCHEMBL4283225 | 0.78 | HTT (1.00) | HTTMAPTLMNAPKMALDH1A1 | |
| SCHEMBL4070310 | 0.78 | HTT (0.61) | HTTMAPTLMNAPKMALDH1A1 | |
| SCHEMBL4284501 | 0.78 | ALDH1A1 (1.00) | HTTMAPTLMNAPKMALDH1A1 | |
| SCHEMBL4066997 | 0.76 | HTT (0.54) | HTTMAPTLMNAPKMALDH1A1 | |
| SCHEMBL4068556 | 0.74 | HTT (0.82) | HTTMAPTLMNAPKMALDH1A1 | |
| SCHEMBL4062560 | 0.74 | MAPT (0.98) | HTTMAPTLMNAPKMALDH1A1 | |
| Hydrochloric Acid SCHEMBL4290512 | 0.74 | MAPT (1.00) | HTTMAPTLMNAPKMALDH1A1 | |
| SCHEMBL4389559 | 0.73 | ALDH1A1 (0.67) | HTTMAPTLMNAPKMALDH1A1 | |
| Hydrochloric Acid SCHEMBL4067028 | 0.72 | ALDH1A1 (0.66) | HTTMAPTLMNAPKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1960777-B1 | SERUM-FREE EXPANSION OF CELLS IN CULTURE | CHOONGWAE PHARMA CORP (KR) | 2009-10-21 | — | — | EP | disclosed |
| WO-2007062243-A9 | SERUM-FREE EXPANSION OF CELLS IN CULTURE | CHOONGWAE PHARMA CORP (KR) | 2008-12-04 | — | — | WO | disclosed |
| EP-1960777-A2 | SERUM-FREE EXPANSION OF CELLS IN CULTURE | Choongwae Pharma Corporation (KR) | 2008-08-27 | — | — | EP | disclosed |
| US-20070128669-A1 | Serum-free expansion of cells in culture | INSTITUTE FOR CHEMICAL GENOMICS (US) | 2007-06-07 | — | — | US | disclosed |
| WO-2007062243-A2 | SERUM-FREE EXPANSION OF CELLS IN CULTURE | CHOONGWAE PHARMA CORPORATION (KR) | 2007-05-31 | — | — | WO | disclosed |