Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | PKM | P14618 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CLK1 | P49759 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4070310 | 0.91 | HTT (0.61) | HTTALDH1A1MAPTLMNAPKM | |
| SCHEMBL4063361 | 0.87 | ALDH1A1 (0.64) | HTTALDH1A1MAPTLMNAPKM | |
| SCHEMBL4244216 | 0.81 | MAPT (0.60) | HTTALDH1A1MAPTLMNAPKM | |
| SCHEMBL4063391 | 0.76 | ALDH1A1 (0.41) | HTTALDH1A1MAPTLMNANPSR1 | |
| SCHEMBL4286778 | 0.76 | ALDH1A1 (0.83) | HTTALDH1A1MAPTLMNAPKM | |
| SCHEMBL4067979 | 0.76 | HTT (0.64) | HTTALDH1A1MAPTLMNAPKM | |
| SCHEMBL4239438 | 0.74 | MAPT (0.49) | HTTALDH1A1MAPTLMNAPKM | |
| SCHEMBL4065608 | 0.70 | HTT (1.00) | HTTALDH1A1MAPTLMNAPKM | |
| SCHEMBL4241354 | 0.70 | ALDH1A1 (0.49) | HTTALDH1A1MAPTLMNAPKM | |
| SCHEMBL4281505 | 0.67 | ALDH1A1 (1.00) | HTTALDH1A1MAPTLMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1960777-B1 | SERUM-FREE EXPANSION OF CELLS IN CULTURE | CHOONGWAE PHARMA CORP (KR) | 2009-10-21 | — | — | EP | disclosed |
| US-20070128669-A1 | Serum-free expansion of cells in culture | INSTITUTE FOR CHEMICAL GENOMICS (US) | 2007-06-07 | — | — | US | disclosed |