SCHEMBL4068458

SCHEMBL4068458

O=C(O)CCCCOCCCC(=O)O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.61
ALDH1A1 P00352 3/20 0.58
TSHR P16473 5/20 0.58
NFKB1 P19838 2/20 0.58
PMP22 Q01453 1/20 0.58
SLC22A6 Q4U2R8 2/20 0.53
GPR84 Q9NQS5 4/20 0.48
FFAR1 O14842 2/20 0.48
FFAR4 Q5NUL3 2/20 0.48
AKR1B1 P15121 1/20 0.48
CYP2D6 P10635 1/20 0.48
FOLH1 Q04609 1/20 0.48
PPARG P37231 5/20 0.46
PPARD Q03181 5/20 0.46
PPARA Q07869 5/20 0.46
HDAC11 Q96DB2 4/20 0.46
TLR2 O60603 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
FABP4 P15090 2/20 0.46
PTPN1 P18031 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16011444 0.97 TSHR (0.63) LMNAALDH1A1TSHRNFKB1PMP22
SCHEMBL6897848 0.97 TSHR (0.63) LMNAALDH1A1TSHRNFKB1PMP22
SCHEMBL6901767 0.97 TSHR (0.63) LMNAALDH1A1TSHRNFKB1PMP22
SCHEMBL6900901 0.97 TSHR (0.63) LMNAALDH1A1TSHRNFKB1PMP22
SCHEMBL8746939 0.97 TSHR (0.63) LMNAALDH1A1TSHRNFKB1PMP22
SCHEMBL446542 0.97 LMNA (0.65) LMNAALDH1A1TSHRNFKB1PMP22
SCHEMBL6367297 0.94 TSHR (0.67) LMNAALDH1A1TSHRNFKB1PMP22
SCHEMBL6901617 0.94 TSHR (0.67) LMNAALDH1A1TSHRNFKB1PMP22
SCHEMBL7748806 0.94 TSHR (0.67) LMNAALDH1A1TSHRNFKB1PMP22
SCHEMBL21357404 0.94 TSHR (0.67) LMNAALDH1A1TSHRNFKB1PMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2110143-A2 Stenoprophiluric matrices, and methods of making and using the same Guritza, Dennis A. (US) 2009-10-21 EP disclosed
EP-1339401-A4 STENOPROPHILURIC MATRICES, AND METHODS OF MAKING AND USING THE SAME GURITZA DENNIS A (US) 2007-03-28 EP disclosed
EP-1339401-A1 STENOPROPHILURIC MATRICES, AND METHODS OF MAKING AND USING THE SAME Guritza, Dennis A. (US) 2003-09-03 EP disclosed
US-6555228-B2 Comprising at least one bio-limiting agent; preventing fouling by applying to an substrate which is prone to biodegredation and corrosion LURITEK, INC. 2003-04-29 US disclosed
EP-0726922-B1 METAL-NITROGEN POLYMER COMPOSITIONS COMPRISING ORGANIC ELECTROPHILES KION CORP (US) 2002-06-12 EP disclosed
WO-2002036112-A1 STENOPROPHILURIC MATRICES, AND METHODS OF MAKING AND USING THE SAME GURITZA DENNIS A (US) 2002-05-10 WO disclosed
US-20020045057-A1 Stenoprophiluric matrices, and methods of making and using the same LURITEK, INC. 2002-04-18 US disclosed
US-6008462-A Mar resistant, corrosion inhibiting, weldable coating containing iron powder for metal substrates MORTON INTERNATIONAL, INC. (US) 1999-12-28 US disclosed
US-5859095-A CONTAINS CHROMIUM TRIOXIDE AND IS FREE OF STRONTIUM CHROMATE; USEFUL FOR DEPOSITING COATINGS ON METALLIC SUBSTRATES MORTON INTERNATIONAL, INC. (US) 1999-01-12 US disclosed
US-5807954-A POLYSILAZANES, POLYBORAZINES, ORGANOALUMINUM POLYMERS, REACTED WITH ISOCYANATES, POLYACRYLATES, POLYIMIDES, ESTERS, POLYURETHANES, MOLDING MATERIALS, COATINGS, CERAMERS LANXIDE TECHNOLOGY COMPANY, LP (US) 1998-09-15 US disclosed
US-5082698-A Aqueous epoxy resin compositions and metal substrates coated therewith MORTON COATINGS, INC. (US) 1992-01-21 US disclosed
US-5001173-A Aqueous epoxy resin compositions and metal substrates coated therewith MORTON COATINGS, INC. (US) 1991-03-19 US disclosed
EP-0396429-A2 Polyurethane-based polymeric materials and biomedical articles and pharmaceutical compositions utilizing the same BIOMEDICAL POLYMERS INTERNATIONAL, LTD. (US) 1990-11-07 EP disclosed
US-4826945-A POLYESTERS, POLYETHERS, POLYURETHANES YISSUM RESEARCH DEVELOPMENT COMPANY (IL) 1989-05-02 US disclosed
EP-0295055-A2 Biodegradable polymeric materials based on polyether glycols, processes for the preparation thereof and surgical articles made therefrom BIOMEDICAL POLYMERS INTERNATIONAL, LTD. (US) 1988-12-14 EP disclosed
EP-0291260-A2 Aqueous epoxy resin compositions and metal substrates coated therewith MORTON INTERNATIONAL, INC. (US) 1988-11-17 EP disclosed
US-4529792-A Reacting diamine with lactic or glycolic acid; then bischloroformate MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-07-16 US disclosed
EP-0030822-B1 SYNTHETIC ABSORBABLE SURGICAL DEVICES OF POLYESTER AMIDES AND PROCESS FOR MAKING THEM MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1983-09-14 EP disclosed
US-4343931-A FILAMENTS, SUTURES, PROSTHETICS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1982-08-10 US disclosed
EP-0030822-A2 Synthetic absorbable surgical devices of polyester amides and process for making them MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1981-06-24 EP disclosed