Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 10/20 | 0.71 |
| ▸ | MMP12 | P39900 | 4/20 | 0.70 |
| ▸ | TAS1R3 | Q7RTX0 | 7/20 | 0.52 |
| ▸ | TAS1R1 | Q7RTX1 | 7/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6024236 | 0.90 | BMP1 (0.57) | BMP1MMP12TAS1R3TAS1R1HDAC3 | |
| SCHEMBL11889610 | 0.87 | BMP1 (0.61) | BMP1MMP12TAS1R3TAS1R1 | |
| SCHEMBL4069000 | 0.87 | BMP1 (0.72) | BMP1MMP12TAS1R3TAS1R1HDAC3 | |
| SCHEMBL16898254 | 0.83 | BMP1 (1.00) | BMP1MMP12 | |
| SCHEMBL16898252 | 0.83 | BMP1 (1.00) | BMP1MMP12 | |
| SCHEMBL16898247 | 0.82 | BMP1 (0.87) | BMP1MMP12 | |
| SCHEMBL16898245 | 0.82 | BMP1 (0.87) | BMP1MMP12 | |
| SCHEMBL16898649 | 0.82 | BMP1 (0.78) | BMP1MMP12 | |
| SCHEMBL16898647 | 0.82 | BMP1 (0.78) | BMP1MMP12 | |
| SCHEMBL21498456 | 0.82 | BMP1 (0.77) | BMP1MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1585757-A4 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2009-04-22 | — | — | EP | claimed |
| JP-2006516120-A | — | — | 2006-06-22 | — | — | JP | claimed |
| EP-1585757-A2 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-10-19 | — | — | EP | claimed |
| WO-2004052919-A2 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-06-24 | — | — | WO | claimed |