Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 12/20 | 0.72 |
| ▸ | MMP12 | P39900 | 5/20 | 0.72 |
| ▸ | TLL1 | O43897 | 1/20 | 0.49 |
| ▸ | TLL2 | Q9Y6L7 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6024195 | 0.90 | BMP1 (0.59) | BMP1MMP12HDAC3TAS1R3TAS1R1 | |
| SCHEMBL4068544 | 0.87 | BMP1 (0.71) | BMP1MMP12HDAC3TAS1R3TAS1R1 | |
| SCHEMBL11889625 | 0.85 | BMP1 (0.59) | BMP1MMP12TLL1TLL2 | |
| SCHEMBL16898498 | 0.82 | BMP1 (1.00) | BMP1MMP12TLL1TLL2 | |
| SCHEMBL16898496 | 0.82 | BMP1 (1.00) | BMP1MMP12TLL1TLL2 | |
| SCHEMBL4069976 | 0.81 | BMP1 (0.53) | BMP1MMP12ALDH1A1TP53HPGD | |
| SCHEMBL1596968 | 0.80 | BMP1 (0.51) | BMP1MMP12 | |
| SCHEMBL1596965 | 0.80 | BMP1 (0.51) | BMP1MMP12 | |
| SCHEMBL6755699 | 0.80 | BMP1 (0.48) | BMP1MMP12TAS1R3TAS1R1 | |
| SCHEMBL7041315 | 0.80 | BMP1 (0.48) | BMP1MMP12TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1585757-A4 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2009-04-22 | — | — | EP | disclosed |
| EP-1585757-A2 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-10-19 | — | — | EP | disclosed |
| WO-2004052919-A2 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-06-24 | — | — | WO | disclosed |