SCHEMBL4068948 — predicted protein targets

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	MAPK13	O15264	5/20	0.39

▸	MAPK12	P53778	5/20	0.39

▸	MAPK11	Q15759	5/20	0.39

▸	MAPK14	Q16539	5/20	0.39

▸	KCNH2	Q12809	1/20	0.39

▸	PRKD3	O94806	1/20	0.33

▸	CLK2	P49760	1/20	0.33

▸	DYRK1A	Q13627	1/20	0.33

▸	PRKD2	Q9BZL6	1/20	0.33

▸	PIM2	Q9P1W9	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL4766490	0.86	MAPK14 (0.44)	MAPK13MAPK12MAPK11MAPK14KCNH2
SCHEMBL5738188	0.81	MAPK13 (0.41)	MAPK13MAPK12MAPK11MAPK14KCNH2
SCHEMBL2718489	0.79	MAPK14 (0.40)	MAPK13MAPK12MAPK11MAPK14KCNH2
SCHEMBL4299724	0.79	MAPK13 (0.33)	MAPK13MAPK12MAPK11MAPK14KCNH2
SCHEMBL2719310	0.78	MAPK14 (0.44)	MAPK13MAPK12MAPK11MAPK14KCNH2
SCHEMBL5332150	0.78	PDE7A (0.33)	MAPK13MAPK12MAPK11MAPK14KCNH2
SCHEMBL5254602	0.78	MAPK14 (0.34)	MAPK13MAPK12MAPK11MAPK14KCNH2
SCHEMBL2720676	0.78	MAPK14 (0.43)	MAPK13MAPK12MAPK11MAPK14KCNH2
SCHEMBL5738681	0.78	MAPK14 (0.46)	MAPK13MAPK12MAPK11MAPK14KCNH2
SCHEMBL5256916	0.78	MAPK14 (0.37)	MAPK13MAPK12MAPK11MAPK14KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-2034838-A2	NOVEL COMPOUNDS	Glaxo Group Limited (GB)	2009-03-18	—	—	EP	disclosed
WO-2007147103-A2	NOVEL COMPOUNDS	GLAXO GROUP LIMITED (GB)	2007-12-21	—	—	WO	disclosed