Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1445312 | 0.84 | AOC3 (0.58) | AOC3KCNA3DRD4LMNACYP2C19 | |
| SCHEMBL29036524 | 0.82 | KMT2A (0.48) | AOC3MAOBLMNACYP2C19GAA | |
| SCHEMBL1251552 | 0.76 | ALDH1A1 (0.52) | AOC3MAOBKCNA3LMNACYP2C19 | |
| SCHEMBL10754135 | 0.76 | AOC3 (0.50) | AOC3KCNA3DRD4LMNACYP2C19 | |
| SCHEMBL2319830 | 0.76 | AOC3 (0.50) | AOC3KCNA3LMNATAAR1ALDH1A1 | |
| SCHEMBL854566 | 0.76 | MAOB (0.48) | MAOBALDH1A1LTA4H | |
| SCHEMBL74275 | 0.75 | MAOB (0.67) | MAOBTAAR1ALDH1A1SMN1; SMN2ALOX15 | |
| SCHEMBL4154296 | 0.75 | AOC3 (0.54) | AOC3KCNA3DRD4LMNAHDAC6 | |
| SCHEMBL1017941 | 0.74 | KCNA3 (0.56) | AOC3KCNA3DRD4HDAC6TAAR1 | |
| SCHEMBL1253670 | 0.74 | AOC3 (0.48) | AOC3KCNA3DRD4LMNAHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1415986-B1 | SPIRO ISOBENZOFURANES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | BANYU PHARMA CO LTD (JP) | 2009-04-08 | — | — | EP | disclosed |
| US-7205417-B2 | Spiro compounds | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-04-17 | — | — | US | disclosed |
| CN-1538956-A | Spiro compounds | ������ҩ��ʽ���� | 2004-10-20 | — | — | CN | disclosed |