SCHEMBL4069043

SCHEMBL4069043

CCN(C(C)C)C(C)C.O=C(O)CCC(C(=O)O)N1C(=O)CCC1=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.44
CYP2C19 P33261 1/20 0.44
ALDH1A1 P00352 3/20 0.43
KDM4E B2RXH2 2/20 0.43
HPGD P15428 2/20 0.43
MAPK1 P28482 2/20 0.43
HSD17B10 Q99714 2/20 0.43
TP53 P04637 1/20 0.43
GLA P06280 1/20 0.43
POLB P06746 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2D6 P10635 1/20 0.43
ALOX12 P18054 1/20 0.43
NFKB1 P19838 1/20 0.43
APEX1 P27695 1/20 0.43
PPM1B O75688 1/20 0.43
PKM P14618 1/20 0.41
MME P08473 1/20 0.35
SLC1A2 P43004 1/20 0.35
FOLH1 Q04609 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1333228 0.85 ALDH1A1 (0.56) CYP1A2CYP2C19ALDH1A1KDM4EHPGD
SCHEMBL631270 0.85 ALDH1A1 (0.56) CYP1A2CYP2C19ALDH1A1KDM4EHPGD
Ethylene Glycol SCHEMBL29002151 0.81 ALDH1A1 (0.51) CYP1A2CYP2C19ALDH1A1KDM4EHPGD
SCHEMBL14674752 0.76 ALDH1A1 (0.50) CYP1A2CYP2C19ALDH1A1KDM4EHPGD
Succinic Acid SCHEMBL31137819 0.75 CYP1A2 (0.47) CYP1A2CYP2C19ALDH1A1KDM4EHPGD
SCHEMBL12100863 0.75 ALDH1A1 (0.53) CYP1A2CYP2C19ALDH1A1KDM4EHPGD
SCHEMBL30773222 0.74 ALDH1A1 (0.49) CYP1A2CYP2C19ALDH1A1KDM4EHPGD
SCHEMBL1226562 0.73 ALDH1A1 (0.54) CYP1A2CYP2C19ALDH1A1KDM4EHPGD
SCHEMBL846234 0.73 ALDH1A1 (0.47) CYP1A2CYP2C19ALDH1A1KDM4EHPGD
SCHEMBL17821007 0.73 ALDH1A1 (0.47) CYP1A2CYP2C19ALDH1A1KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2009505946-A 2009-02-12 JP claimed
EP-1904460-A1 MULTIDENTATE AZA LIGANDS ABLE TO COMPLEX METAL IONS AND THE USE THEREOF IN DIAGNOSTICS AND THERAPY BRACCO IMAGING S.p.A. (IT) 2008-04-02 EP claimed
WO-2006136564-A1 MULTIDENTATE AZA LIGANDS ABLE TO COMPLEX METAL IONS AND THE USE THEREOF IN DIAGNOSTICS AND THERAPY BRACCO IMAGING S.P.A. (IT) 2006-12-28 WO claimed
EP-1904460-A1 MULTIDENTATE AZA LIGANDS ABLE TO COMPLEX METAL IONS AND THE USE THEREOF IN DIAGNOSTICS AND THERAPY BRACCO IMAGING S.p.A. (IT) 2008-04-02 EP disclosed
WO-2006136564-A9 MULTIDENTATE AZA LIGANDS ABLE TO COMPLEX METAL IONS AND THE USE THEREOF IN DIAGNOSTICS AND THERAPY BRACCO IMAGING SPA (IT) 2008-02-07 WO disclosed
WO-2006136564-A1 MULTIDENTATE AZA LIGANDS ABLE TO COMPLEX METAL IONS AND THE USE THEREOF IN DIAGNOSTICS AND THERAPY BRACCO IMAGING S.P.A. (IT) 2006-12-28 WO disclosed