SCHEMBL631270

SCHEMBL631270

O=C(O)CCC(C(=O)O)N1C(=O)CCC1=O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.56
KDM4E B2RXH2 2/20 0.56
HPGD P15428 2/20 0.56
MAPK1 P28482 2/20 0.56
HSD17B10 Q99714 2/20 0.56
TP53 P04637 1/20 0.56
GLA P06280 1/20 0.56
POLB P06746 1/20 0.56
CYP3A4 P08684 1/20 0.56
CYP2D6 P10635 1/20 0.56
ALOX12 P18054 1/20 0.56
NFKB1 P19838 1/20 0.56
APEX1 P27695 1/20 0.56
CYP1A2 P05177 3/20 0.55
CYP2C19 P33261 1/20 0.55
PPM1B O75688 1/20 0.54
PKM P14618 1/20 0.53
FOLH1 Q04609 5/20 0.41
TET2 Q6N021 3/20 0.39
KDM4A O75164 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1333228 1.00 ALDH1A1 (0.56) ALDH1A1KDM4EHPGDMAPK1HSD17B10
Ethylene Glycol SCHEMBL29002151 0.95 ALDH1A1 (0.51) ALDH1A1KDM4EHPGDMAPK1HSD17B10
SCHEMBL14674752 0.89 ALDH1A1 (0.50) ALDH1A1KDM4EHPGDMAPK1HSD17B10
Succinic Acid SCHEMBL31137819 0.89 CYP1A2 (0.47) ALDH1A1KDM4EHPGDMAPK1HSD17B10
SCHEMBL30773222 0.87 ALDH1A1 (0.49) ALDH1A1KDM4EHPGDMAPK1HSD17B10
SCHEMBL1226562 0.86 ALDH1A1 (0.54) ALDH1A1KDM4EHPGDMAPK1HSD17B10
SCHEMBL17821007 0.86 ALDH1A1 (0.47) ALDH1A1KDM4EHPGDMAPK1HSD17B10
SCHEMBL846234 0.86 ALDH1A1 (0.47) ALDH1A1KDM4EHPGDMAPK1HSD17B10
SCHEMBL4069043 0.85 CYP1A2 (0.44) ALDH1A1KDM4EHPGDMAPK1HSD17B10
SCHEMBL8510382 0.81 ALDH1A1 (0.53) ALDH1A1KDM4EHPGDMAPK1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 232 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4580690-B1 BIODEGRADABLE LUNG SEALANTS ETHICON INC (US) 2026-03-18 EP claimed
EP-4291256-B1 TWO COMPONENT SEALING SYSTEMS INCLUDING SYNTHETIC MATRICES AND BIOSYNTHETIC ADHESIVES ETHICON INC (US) 2026-02-18 EP claimed
EP-3600189-B1 SKIN CLOSURE SYSTEMS AND DEVICES OF IMPROVED FLEXIBILITY AND STRETCHABILITY FOR BENDABLE JOINTS ETHICON INC (US) 2026-02-18 EP claimed
US-12329853-B2 Compositions and methods for treating ocular diseases OCULAR THERAPEUTIX, INC. (US) 2025-06-17 US claimed
US-12297335-B2 Radiopaque multi-armed polymers and compositions, systems and methods pertaining to the same BOSTON SCIENTIFIC SCIMED, INC. (US) 2025-05-13 US claimed
CN-118662684-B Preparation method of biological antibacterial adhesive and application of obtained adhesive 卓阮医疗科技(苏州)有限公司 2025-04-25 CN claimed
WO-2024215649-A1 OCULAR IMPLANT COMPRISING AXITINIB POLYMORPH IV OCULAR THERAPEUTIX, INC. (US) 2024-10-17 WO claimed
EP-3515406-B1 INTRACAMERAL DRUG DELIVERY DEPOTS INCEPT LLC (US) 2024-07-24 EP claimed
EP-4344745-A2 SUSTAINED RELEASE BIODEGRADABLE INTRACANALICULAR INSERTS COMPRISING A HYDROGEL AND CYCLOSPORINE Ocular Therapeutix, Inc. (US) 2024-04-03 EP claimed
EP-3973952-B1 SUSTAINED RELEASE BIODEGRADABLE INTRACANALICULAR INSERTS COMPRISING A HYDROGEL AND CYCLOSPORINE OCULAR THERAPEUTIX INC (US) 2024-02-14 EP claimed
EP-3518993-B1 SCAFFOLDS WITH CHANNELS FOR JOINING LAYERS OF TISSUE AT DISCRETE POINTS ETHICON INC (US) 2020-10-28 EP claimed
CN-110461285-A Skin closure system and device for improved flexibility and stretchability of a flexible joint ETHICON INC 2019-11-15 CN claimed
CN-105498559-B Composite membrane based on functional protein 中国科学院烟台海岸带研究所 2018-10-16 CN claimed
CN-105498559-A Composite membrane based on functional protein YANTAI INST COASTAL ZONE RES CAS 2016-04-20 CN claimed
WO-2014053873-A1 POLYMERIC PRODRUG CONJUGATES Piramal Enterprises Limited (IN) 2014-04-10 WO claimed
US-8617584-B2 Adhesive tissue repair patch and collagen sheets ANGIODEVICE INTERNATIONAL GMBH (CH) 2013-12-31 US claimed
EP-2358412-B1 AUTO-SEALANT MATRIX FOR TISSUE REPAIR SOFRADIM PRODUCTION (FR) 2012-07-11 EP claimed
EP-1935426-B1 Prevention of biofilm formation using pegylated blood products CANADIAN BLOOD SERVICES (CA) 2012-04-18 EP claimed
US-20100233246-A1 ADHESIVE TISSUE REPAIR PATCH AND COLLAGEN SHEETS ANGIOTECH PHARMACEUTICALS (US), INC. (US) 2010-09-16 US claimed
EP-0696617-B1 Method of controlling structure stability of collagen fibers produced from solutions or dispersions treated with sodium hydroxide for infectious agent deactivation COHESION TECH INC (US) 2001-07-11 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12329853-B2 Compositions and methods for treating ocular diseases PDE6C, PDE6H, PDE6A ALDH1A1 2175/4885KDM4E 3618/4885HPGD 461/4885
US-20100233246-A1 ADHESIVE TISSUE REPAIR PATCH AND COLLAGEN SHEETS COL2A1, COL14A1, COL1A1 ALDH1A1 4071/4885KDM4E 794/4885HPGD 2063/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.