Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16445515 | 0.75 | ALDH1A1 (0.31) | ALDH1A1L3MBTL1 | |
| SCHEMBL4069044 | 0.72 | CTSB (0.38) | ALDH1A1L3MBTL1 | |
| SCHEMBL337653 | 0.63 | CTSB (0.37) | ALDH1A1L3MBTL1 | |
| SCHEMBL11387535 | 0.63 | CTSB (0.37) | ALDH1A1L3MBTL1 | |
| SCHEMBL680381 | 0.62 | ALDH1A1 (0.37) | ALDH1A1L3MBTL1 | |
| SCHEMBL11889925 | 0.62 | ALDH1A1 (0.38) | ALDH1A1L3MBTL1 | |
| SCHEMBL4062012 | 0.62 | GRM5 (0.37) | — | |
| SCHEMBL9873974 | 0.61 | ALDH1A1 (0.36) | ALDH1A1L3MBTL1 | |
| SCHEMBL11889919 | 0.60 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1 | |
| SCHEMBL4066201 | 0.59 | GRM5 (0.42) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2032535-B1 | SPIROCYCLIC NITRILES AS PROTEASE INHIBITORS | SANOFI SA (FR) | 2012-08-01 | — | — | EP | claimed |
| EP-2032535-A1 | SPIROCYCLIC NITRILES AS PROTEASE INHIBITORS | Sanofi-Aventis (FR) | 2009-03-11 | — | — | EP | claimed |
| WO-2007137738-A1 | SPIROCYCLIC NITRILES AS PROTEASE INHIBITORS | SANOFI-AVENTIS (DE) | 2007-12-06 | — | — | WO | claimed |
| EP-2520568-A1 | Spirocyclic nitriles as inhibitors of protease | SANOFI (FR) | 2012-11-07 | — | — | EP | disclosed |
| EP-2032535-B1 | SPIROCYCLIC NITRILES AS PROTEASE INHIBITORS | SANOFI SA (FR) | 2012-08-01 | — | — | EP | disclosed |
| EP-2032535-A1 | SPIROCYCLIC NITRILES AS PROTEASE INHIBITORS | Sanofi-Aventis (FR) | 2009-03-11 | — | — | EP | disclosed |
| WO-2007137738-A1 | SPIROCYCLIC NITRILES AS PROTEASE INHIBITORS | SANOFI-AVENTIS (DE) | 2007-12-06 | — | — | WO | disclosed |