SCHEMBL406912

SCHEMBL406912

CCC=Cc1ccccc1OP(=O)(O)O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 5/20 0.60
INPPL1 O15357 4/20 0.44
INPP5A Q14642 3/20 0.44
INPP5B P32019 2/20 0.44
KDM4E B2RXH2 3/20 0.44
ALDH1A1 P00352 2/20 0.44
USP2 O75604 1/20 0.44
HPGD P15428 1/20 0.44
PDE3A Q14432 1/20 0.44
HSD17B10 Q99714 1/20 0.44
NFE2L2 Q16236 2/20 0.41
TFEB P19484 1/20 0.39
AKT1 P31749 1/20 0.39
GRIK1 P39086 1/20 0.36
GRIK2 Q13002 1/20 0.36
GRIK3 Q13003 1/20 0.36
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
ATM Q13315 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL406911 0.87 SRC (0.42) SRCKDM4EALDH1A1HPGDNFE2L2
SCHEMBL13158799 0.85 SRC (0.62) SRCINPPL1INPP5AINPP5BKDM4E
SCHEMBL13158806 0.81 SRC (0.66) SRCINPPL1INPP5AINPP5BKDM4E
Ether SCHEMBL21144482 0.80 SRC (0.55) SRCINPPL1INPP5AINPP5BKDM4E
Ether SCHEMBL22721324 0.78 SRC (0.53) SRCINPPL1INPP5AINPP5BKDM4E
SCHEMBL10781099 0.77 NFE2L2 (0.41) KDM4EALDH1A1NFE2L2TFEBLMNA
SCHEMBL30579741 0.77 SRC (0.64) SRCINPPL1INPP5AINPP5BKDM4E
SCHEMBL3994776 0.77 SRC (0.64) SRCINPPL1INPP5AINPP5BKDM4E
SCHEMBL13158795 0.77 SRC (0.48) SRCINPPL1INPP5AINPP5BKDM4E
SCHEMBL3514846 0.75 SRC (1.00) SRCINPPL1INPP5AINPP5BKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2392615-B1 POLYOLEFIN RESIN COMPOSITION ADEKA CORP (JP) 2016-12-21 EP disclosed
US-20120022212-A1 POLYOLEFIN RESIN COMPOSITION ADEKA CORPORATION (JP) 2012-01-26 US disclosed
EP-2392615-A1 POLYOLEFIN RESIN COMPOSITION Adeka Corporation (JP) 2011-12-07 EP disclosed
US-20110288216-A1 POLYOLEFIN-BASED RESIN COMPOSITION FOR FOOD, MEDICAL, AND MUNICIPAL WATER PIPE APPLICATIONS ADEKA CORPORATION (JP) 2011-11-24 US disclosed