SCHEMBL406911

SCHEMBL406911

CC/C=C/c1ccccc1OP(=O)(Oc1ccccc1/C=C/CC)Oc1ccccc1/C=C/CC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 2/20 0.42
NFE2L2 Q16236 4/20 0.39
TFEB P19484 1/20 0.38
KDM4E B2RXH2 3/20 0.37
ALDH1A1 P00352 2/20 0.36
TSHR P16473 1/20 0.36
TRPA1 O75762 1/20 0.36
GRIK1 P39086 1/20 0.35
GRIK2 Q13002 1/20 0.35
GRIK3 Q13003 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
HPGD P15428 1/20 0.35
HTT P42858 1/20 0.35
CDK4 P11802 2/20 0.35
CCND1 P24385 2/20 0.35
CCNB2 O95067 1/20 0.35
CDK1 P06493 1/20 0.35
CCNB1 P14635 1/20 0.35
CCNB3 Q8WWL7 1/20 0.35
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL406912 0.87 SRC (0.60) SRCNFE2L2TFEBKDM4EALDH1A1
SCHEMBL7210055 0.80 SRC (0.46) SRCNFE2L2TFEBKDM4ETRPA1
SCHEMBL7210051 0.80 SRC (0.46) SRCNFE2L2TFEBKDM4ETRPA1
SCHEMBL10781099 0.80 NFE2L2 (0.41) NFE2L2TFEBKDM4EALDH1A1TSHR
SCHEMBL29372144 0.78 NFE2L2 (0.58) NFE2L2TFEBKDM4EALDH1A1TSHR
SCHEMBL257125 0.78 NFE2L2 (0.58) NFE2L2TFEBKDM4EALDH1A1TSHR
SCHEMBL5085210 0.78 NFE2L2 (0.58) NFE2L2TFEBKDM4EALDH1A1TSHR
SCHEMBL9898069 0.76 NFE2L2 (0.39) NFE2L2TFEBKDM4EALDH1A1TSHR
SCHEMBL9019348 0.75 NFE2L2 (0.59) SRCNFE2L2ALDH1A1TRPA1LMNA
SCHEMBL73693 0.75 AR (0.46) NFE2L2KDM4EALDH1A1TSHRTRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2392615-B1 POLYOLEFIN RESIN COMPOSITION ADEKA CORP (JP) 2016-12-21 EP disclosed
US-20120022212-A1 POLYOLEFIN RESIN COMPOSITION ADEKA CORPORATION (JP) 2012-01-26 US disclosed
EP-2392615-A1 POLYOLEFIN RESIN COMPOSITION Adeka Corporation (JP) 2011-12-07 EP disclosed
US-20110288216-A1 POLYOLEFIN-BASED RESIN COMPOSITION FOR FOOD, MEDICAL, AND MUNICIPAL WATER PIPE APPLICATIONS ADEKA CORPORATION (JP) 2011-11-24 US disclosed