Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.71 |
| ▸ | KLK7 | P49862 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.67 |
| ▸ | RELA | Q04206 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29086702 | 1.00 | EPHX2 (0.71) | EPHX2KLK7ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL29086653 | 0.98 | KLK7 (0.72) | EPHX2KLK7ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL28421952 | 0.91 | EPHX2 (0.68) | EPHX2KLK7ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL28424785 | 0.89 | MEN1 (0.67) | EPHX2KLK7ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL30979855 | 0.89 | EPHX2 (0.65) | EPHX2KLK7ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL11731614 | 0.86 | ALDH1A1 (0.70) | EPHX2KLK7ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL1947822 | 0.85 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2NPC1HPGDNFKB1 | |
| SCHEMBL11730422 | 0.84 | ALDH1A1 (0.67) | KLK7ALDH1A1SMN1; SMN2NPC1HPGD | |
| SCHEMBL9845442 | 0.84 | LDLR (0.69) | KLK7ALDH1A1SMN1; SMN2NPC1HPGD | |
| SCHEMBL6508976 | 0.84 | KMT2A (0.67) | EPHX2KLK7ALDH1A1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116874448-A | Hydrazine and air mediated non-activated C (sp 3 ) Method for adding-H bond to electron-deficient olefin | 昆明理工大学 | 2023-10-13 | — | — | CN | disclosed |
| CN-115556441-A | Decorative film and method for producing decorative molded body using same | 日本聚丙烯株式会社 | 2023-01-03 | — | — | CN | disclosed |
| CN-115556446-A | Decorative film and method for producing decorative molded body using same | 日本聚丙烯株式会社 | 2023-01-03 | — | — | CN | disclosed |
| EP-3884934-A1 | MODULATORS OF THE PROSTACYCLIN (PGI2) RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | Arena Pharmaceuticals, Inc. (US) | 2021-09-29 | — | — | EP | disclosed |
| CN-111386185-A | Decorative film and method for producing decorative molded body using same | 日本聚丙烯株式会社 | 2020-07-07 | — | — | CN | disclosed |
| EP-1415986-B1 | SPIRO ISOBENZOFURANES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | BANYU PHARMA CO LTD (JP) | 2009-04-08 | — | — | EP | disclosed |
| US-7205417-B2 | Spiro compounds | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-04-17 | — | — | US | disclosed |