Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDLR | P01130 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.58 |
| ▸ | RELA | Q04206 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8388737 | 0.87 | KMT2A (0.72) | LDLRALDH1A1KMT2AMAPK1NPSR1 | |
| SCHEMBL29086653 | 0.85 | KLK7 (0.72) | LDLRALDH1A1KMT2AMAPK1NPSR1 | |
| SCHEMBL22475217 | 0.84 | KLK7 (0.79) | ALDH1A1KMT2ASMN1; SMN2MEN1MAPT | |
| SCHEMBL11730422 | 0.84 | ALDH1A1 (0.67) | LDLRALDH1A1KMT2AMAPK1NPSR1 | |
| SCHEMBL4069437 | 0.84 | EPHX2 (0.71) | LDLRALDH1A1KMT2AMAPK1NPSR1 | |
| SCHEMBL29086702 | 0.84 | EPHX2 (0.71) | LDLRALDH1A1KMT2AMAPK1NPSR1 | |
| SCHEMBL13167582 | 0.83 | CNR2 (0.62) | LDLRALDH1A1KMT2AMAPK1NPSR1 | |
| SCHEMBL11731614 | 0.83 | ALDH1A1 (0.70) | LDLRALDH1A1KMT2AMAPK1NPSR1 | |
| SCHEMBL1948582 | 0.83 | ALDH1A1 (0.64) | ALDH1A1KMT2AMAPK1NPSR1HTT | |
| SCHEMBL5647839 | 0.82 | EPHX2 (0.73) | LDLRKMT2ANPC1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409312-A2 | High-fluidity polycarbonates and process for preparing them | ENICHEM S.p.A. (IT) | 1991-01-23 | — | — | EP | claimed |
| EP-0409312-A2 | High-fluidity polycarbonates and process for preparing them | ENICHEM S.p.A. (IT) | 1991-01-23 | — | — | EP | disclosed |