Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 2/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | LTK | P29376 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | PRKX | P51817 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | NUDT1 | P36639 | 3/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 7/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.34 |
| ▸ | TRAP1 | Q12931 | 2/20 | 0.34 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL841314 | 0.83 | JAK2 (0.43) | JAK2PDE10AKDM4EALDH1A1HPGD | |
| SCHEMBL7859414 | 0.81 | JAK2 (0.38) | JAK2PDE10AKDM4EALDH1A1HPGD | |
| SCHEMBL7865987 | 0.81 | JAK2 (0.38) | JAK2PDE10AKDM4EALDH1A1HPGD | |
| SCHEMBL4063510 | 0.81 | NUDT1 (0.38) | JAK2PDE10AKDM4EALDH1A1HPGD | |
| SCHEMBL2253889 | 0.79 | NUDT1 (0.37) | JAK2PDE10AKDM4EALDH1A1HPGD | |
| SCHEMBL7867120 | 0.78 | HSP90AB1 (0.42) | JAK2PDE10AKDM4EHSP90AB1 | |
| SCHEMBL9641238 | 0.75 | — | — | |
| SCHEMBL2254257 | 0.72 | NUDT1 (0.48) | PDE10ANUDT1 | |
| SCHEMBL7870509 | 0.69 | JAK1 (0.50) | JAK2PDE10AKDM4EALDH1A1HPGD | |
| SCHEMBL841386 | 0.67 | HSP90AB1 (0.39) | JAK2PDE10AHSP90AB1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1330458-B1 | N-( 1,2,4 TRIAZOLOAZINYL) THIOPHENESULFONAMIDE COMPOUNDS AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2009-06-03 | — | — | EP | disclosed |
| US-20020094935-A1 | N-([1,2,4] triazoloazinyl) thiophenesulfonamide compounds and their use as herbicides | DOW AGROSCIENCES LLC | 2002-07-18 | — | — | US | disclosed |
| EP-0877745-B1 | N-( 1,2,4] TRIAZOLOAZINYL)BENZENESULFONAMIDE AND PYRIDINESULFONAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2001-07-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020094935-A1 | N-([1,2,4] triazoloazinyl) thiophenesulfonamide compounds and their use as herbicides | PNPO, NAT1, DDT | JAK2 2415/4885PDE10A 4468/4885KDM4E 1222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.