Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 2/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 7/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 2/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
| ▸ | LTK | P29376 | 1/20 | 0.31 |
| ▸ | PRKX | P51817 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.31 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.31 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.31 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL841314 | 0.81 | JAK2 (0.43) | JAK2HSP90AB1PDE10AJAK1KDM4E | |
| SCHEMBL4069697 | 0.81 | JAK2 (0.39) | JAK2HSP90AB1PDE10AJAK1KDM4E | |
| SCHEMBL7859414 | 0.80 | JAK2 (0.38) | JAK2HSP90AB1PDE10AJAK1KDM4E | |
| SCHEMBL4063510 | 0.80 | NUDT1 (0.38) | JAK2HSP90AB1PDE10AJAK1KDM4E | |
| SCHEMBL20785736 | 0.80 | — | — | |
| SCHEMBL7867120 | 0.76 | HSP90AB1 (0.42) | JAK2HSP90AB1PDE10AKDM4EP2RX3 | |
| SCHEMBL7870509 | 0.68 | JAK1 (0.50) | JAK2PDE10AJAK1KDM4EALDH1A1 | |
| SCHEMBL7042523 | 0.67 | PDE10A (0.44) | JAK2HSP90AB1PDE10AJAK1KDM4E | |
| SCHEMBL16361227 | 0.66 | HSP90AB1 (0.44) | JAK2HSP90AB1PDE10AJAK1KDM4E | |
| SCHEMBL841386 | 0.66 | HSP90AB1 (0.39) | JAK2HSP90AB1PDE10AP2RX3P2RX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0877745-B1 | N-( 1,2,4] TRIAZOLOAZINYL)BENZENESULFONAMIDE AND PYRIDINESULFONAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2001-07-25 | — | — | EP | disclosed |