Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1807070 | 0.81 | TTR (0.50) | CA1CA2CA9CDK2TTR | |
| SCHEMBL294489 | 0.81 | CA2 (0.53) | CA1CA2CA9CDK2TTR | |
| SCHEMBL2534154 | 0.81 | CA2 (0.32) | CA1CA2CA9CDK2TTR | |
| SCHEMBL3133065 | 0.77 | CDK2 (0.46) | CA1CA2CA9CDK2TTR | |
| SCHEMBL29904571 | 0.77 | CDK2 (0.46) | CA1CA2CA9CDK2TTR | |
| SCHEMBL2318595 | 0.73 | CYP1A2 (0.32) | — | |
| SCHEMBL18020591 | 0.71 | CYP1A2 (0.54) | CA1CA2CA9CDK2TTR | |
| SCHEMBL57524 | 0.70 | CA1 (0.63) | CA1CA2CA9ALDH1A1HSD17B10 | |
| SCHEMBL31605318 | 0.70 | CA1 (0.63) | CA1CA2CA9ALDH1A1HSD17B10 | |
| SCHEMBL29409606 | 0.70 | CA1 (0.63) | CA1CA2CA9ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117120422-A | Substituted naphthyl P38 alpha mitogen-activated protein kinase inhibitors | GEN1E生命科学公司 | 2023-11-24 | — | — | CN | disclosed |
| EP-2036888-A1 | Naphthyl-substituted sulfonamides | Laboratorios del Dr. Esteve S.A. (ES) | 2009-03-18 | — | — | EP | disclosed |