Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MIF | P14174 | 2/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL405756 | 0.85 | L3MBTL1 (0.37) | L3MBTL1ALDH1A1CYP1A2CYP2C19KMT2A | |
| SCHEMBL406185 | 0.85 | L3MBTL1 (0.41) | L3MBTL1ALDH1A1CYP1A2CYP2C19KMT2A | |
| SCHEMBL406753 | 0.79 | KDM4E (0.41) | L3MBTL1ALDH1A1CYP1A2CYP2C19KMT2A | |
| SCHEMBL17290729 | 0.79 | MIF (0.34) | ALDH1A1CYP1A2CYP2C19KMT2ACYP2C9 | |
| SCHEMBL13784463 | 0.76 | L3MBTL1 (0.45) | L3MBTL1ALDH1A1CYP1A2CYP2C19KMT2A | |
| SCHEMBL8261357 | 0.75 | L3MBTL1 (0.56) | L3MBTL1ALDH1A1CYP1A2CYP2C19KMT2A | |
| SCHEMBL16586280 | 0.70 | L3MBTL1 (0.37) | L3MBTL1ALDH1A1CYP1A2CYP2C19KMT2A | |
| SCHEMBL13784457 | 0.70 | RECQL (0.33) | L3MBTL1MAPK8RECQL | |
| SCHEMBL17295183 | 0.69 | ALDH1A1 (0.31) | ALDH1A1CYP1A2CYP2C19KMT2ACYP2C9 | |
| SCHEMBL406709 | 0.69 | MIF (0.33) | ALDH1A1CYP1A2CYP2C19KMT2ACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9695126-B2 | Fungicide pyrazole carboxamides derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2017-07-04 | — | — | US | disclosed |
| US-20160297766-A1 | FUNGICIDE PYRAZOLE CARBOXAMIDES DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-10-13 | — | — | US | disclosed |
| US-9398767-B2 | Fungicide pyrazole carboxamides derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-07-26 | — | — | US | disclosed |
| US-8772266-B2 | Fungicide pyrazole carboxamides derivates | BAYER CROPSCIENCE AG (DE) | 2014-07-08 | — | — | US | disclosed |
| US-20140148411-A1 | FUNGICIDE PYRAZOLE CARBOXAMIDES DERIVATIVES | BAYER CROPSCIENCE AG | 2014-05-29 | — | — | US | disclosed |
| US-20120065164-A1 | FUNGICIDE PYRAZOLE CARBOXAMIDES DERIVATES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140148411-A1 | FUNGICIDE PYRAZOLE CARBOXAMIDES DERIVATIVES | CASP5, CBR3, CYP3A5 | L3MBTL1 2440/4885ALDH1A1 4202/4885CYP1A2 48/4885 |
| US-20160297766-A1 | FUNGICIDE PYRAZOLE CARBOXAMIDES DERIVATIVES | CASP5, CBR3, CYP3A5 | L3MBTL1 2440/4885ALDH1A1 4202/4885CYP1A2 48/4885 |
| US-20120065164-A1 | FUNGICIDE PYRAZOLE CARBOXAMIDES DERIVATES | CASP5, CTRL, CBR3 | L3MBTL1 1962/4885ALDH1A1 4241/4885CYP1A2 57/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.