Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNK2 | Q07912 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4065196 | 0.88 | IGF1R (0.37) | TNK2 | |
| SCHEMBL400013 | 0.87 | TNK2 (0.32) | TNK2 | |
| SCHEMBL4065777 | 0.86 | TNK2 (0.34) | TNK2 | |
| SCHEMBL4070802 | 0.86 | PIM1 (0.31) | — | |
| SCHEMBL4066036 | 0.84 | EGFR (0.32) | — | |
| SCHEMBL401887 | 0.83 | IGF1R (0.37) | TNK2 | |
| SCHEMBL4072094 | 0.82 | — | — | |
| SCHEMBL1129010 | 0.79 | TNK2 (0.45) | TNK2 | |
| SCHEMBL400401 | 0.77 | TNK2 (0.36) | TNK2 | |
| SCHEMBL396742 | 0.76 | PIM1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1740591-B1 | 6,6-BICYCLIC RING SUBSTITUTED HETEROBICYCLIC PROTEIN KINASE INHIBITORS | OSI PHARM INC (US) | 2009-06-17 | — | — | EP | claimed |