Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MMP1 | P03956 | 2/20 | 0.49 |
| ▸ | PLK1 | P53350 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MPO | P05164 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | KDM5A | P29375 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4411549 | 0.92 | CA1 (0.56) | CA1CA2ALDH1A1MAPTMAPK1 | |
| SCHEMBL4418967 | 0.87 | MMP3 (0.55) | CA1CA2ALDH1A1MAPTMAPK1 | |
| SCHEMBL31270955 | 0.87 | L3MBTL1 (0.67) | ALDH1A1MAPTHTTL3MBTL1LMNA | |
| SCHEMBL18068446 | 0.86 | CA1 (0.66) | CA1CA2ALDH1A1MAPTMAPK1 | |
| SCHEMBL3267877 | 0.83 | HDAC1 (0.63) | ALDH1A1MAPK1HTTL3MBTL1CYP3A4 | |
| SCHEMBL10762321 | 0.83 | PLK1 (0.65) | CA1CA2ALDH1A1MAPTMAPK1 | |
| SCHEMBL4411547 | 0.82 | MMP3 (0.54) | ALDH1A1MAPTMMP1L3MBTL1CYP3A4 | |
| Hydrochloric Acid SCHEMBL5639911 | 0.81 | HDAC1 (0.61) | ALDH1A1MAPK1HTTL3MBTL1CYP3A4 | |
| SCHEMBL6539464 | 0.81 | MAPT (0.69) | CA1CA2ALDH1A1MAPTMAPK1 | |
| SCHEMBL4414363 | 0.81 | GAA (0.51) | MAPTL3MBTL1CYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009155362-A1 | SMALL MOLECULE HEMATOPOIETIC GROWTH FACTOR MIMETIC COMPOUNDS AND THEIR USES | LIGAND PHARMACEUTICALS INC. (US) | 2009-12-23 | — | — | WO | disclosed |