SCHEMBL4072185

SCHEMBL4072185

c1ccc(-c2cccc3c2Nc2ccccc2O3)nc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 6/20 0.47
KDM4E B2RXH2 6/20 0.38
LMNA P02545 3/20 0.38
CCR1 P32246 2/20 0.38
CCR5 P51681 2/20 0.38
CCR8 P51685 2/20 0.38
CYP1A2 P05177 1/20 0.38
POLB P06746 1/20 0.38
METAP1 P53582 1/20 0.38
BLM P54132 1/20 0.38
HIF1A Q16665 1/20 0.38
DOHH Q9BU89 1/20 0.38
P4HTM Q9NXG6 1/20 0.38
TP53 P04637 4/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
MAPK1 P28482 2/20 0.38
ALOX15 P16050 2/20 0.38
HTT P42858 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30462892 1.00 ALOX5 (0.47) ALOX5KDM4ELMNACCR1CCR5
SCHEMBL18048017 0.84 ALOX5 (0.50) ALOX5CYP1A2POLBTP53SMN1; SMN2
SCHEMBL4074615 0.82 ALOX5 (0.47) ALOX5KDM4ELMNACCR1CCR5
SCHEMBL27903683 0.81 ALOX5 (0.41) ALOX5KDM4ELMNACYP1A2SMN1; SMN2
SCHEMBL28562737 0.79 ALOX5 (0.44) ALOX5CYP1A2POLBSMN1; SMN2TDP1
SCHEMBL28363259 0.79 ALOX5 (0.43) ALOX5KDM4ELMNACCR1CCR5
SCHEMBL29390749 0.79 ALOX5 (0.43) ALOX5KDM4ELMNACCR1CCR5
SCHEMBL18076935 0.78 ALOX5 (0.43) ALOX5KDM4ELMNACCR1CCR5
SCHEMBL23322424 0.78 ALOX5 (0.43) ALOX5CYP1A2POLBBLMTP53
SCHEMBL31059186 0.78 ALOX5 (0.43) ALOX5CYP1A2POLBBLMTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110867587-B Neutral water system mixed liquid flow battery with high power and long service life based on pyridylphenoxazine 常州大学 2022-03-01 CN claimed
CN-110867587-A Neutral water system mixed liquid flow battery with high power and long service life based on pyridylphenoxazine 常州大学 2020-03-06 CN claimed
CN-110867587-B Neutral water system mixed liquid flow battery with high power and long service life based on pyridylphenoxazine 常州大学 2022-03-01 CN disclosed
CN-110867587-B Neutral water system mixed liquid flow battery with high power and long service life based on pyridylphenoxazine 常州大学 2022-03-01 CN disclosed
CN-110867587-B Neutral water system mixed liquid flow battery with high power and long service life based on pyridylphenoxazine 常州大学 2022-03-01 CN disclosed
CN-110867587-A Neutral water system mixed liquid flow battery with high power and long service life based on pyridylphenoxazine 常州大学 2020-03-06 CN disclosed
CN-110867587-A Neutral water system mixed liquid flow battery with high power and long service life based on pyridylphenoxazine 常州大学 2020-03-06 CN disclosed
CN-110867587-A Neutral water system mixed liquid flow battery with high power and long service life based on pyridylphenoxazine 常州大学 2020-03-06 CN disclosed
EP-3268489-A1 FLUOROGENIC AND CHROMOGENIC SUBSTRATE LI-COR, INC. (US) 2018-01-17 EP disclosed
US-9632034-B2 Fluorogenic and chromogenic substrate LI-COR, INC. (US) 2017-04-25 US disclosed
WO-2016149127-A1 FLUOROGENIC AND CHROMOGENIC SUBSTRATE LI-COR, INC. (US) 2016-09-22 WO disclosed
EP-1874731-A2 QUINOBENZOXAZINE ANALOGS AND METHODS OF USING THEREOF Cylene Pharmaceuticals, Inc. (US) 2008-01-09 EP disclosed
US-7176307-B2 Organometal complex, electroluminescence material using the complex, and electroluminescence element using the complex SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2007-02-13 US disclosed
US-20060264634-A1 Quinobenzoxazine analogs and methods of using thereof CYLENE PHARMACEUTICALS, INC. 2006-11-23 US disclosed
WO-2006113509-A2 QUINOBENZOXAZINE ANALOGS AND METHODS OF USING THEREOF CYLENE PHARMACEUTICALS, INC. (US) 2006-10-26 WO disclosed
US-20060106211-A1 Organometal complex, electroluminescence material using the complex, and electroluminescence element using the complex SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2006-05-18 US disclosed
US-7041390-B2 Organometal complex, electroluminescence material using the complex, and electroluminescence element using the complex SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2006-05-09 US disclosed
CN-1751055-A Organic metal complex, electroluminescent material using the complex and ectroluminescent element using the complex SEMICONDUCTOR ENERGY LAB (JP) 2006-03-22 CN disclosed
EP-1598361-A1 ORGANIC METAL COMPLEX, ELECTROLUMINESCENT MATERIAL USING THE COMPLEX AND ECTROLUMINESCENT ELEMENT USING THE COMPLEX SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2005-11-23 EP disclosed
US-20050006625-A1 Organometal complex, electroluminescence material using the complex, and electroluminescence element using the complex SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2005-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060264634-A1 Quinobenzoxazine analogs and methods of using thereof CYP2W1, NQO2, UGT2B7 ALOX5 329/4885KDM4E 1852/4885LMNA 2466/4885
US-20050006625-A1 Organometal complex, electroluminescence material using the complex, and electroluminescence element using the complex HSF1, ELP1, RPL19 ALOX5 1416/4885KDM4E 1999/4885LMNA 4376/4885
US-20060106211-A1 Organometal complex, electroluminescence material using the complex, and electroluminescence element using the complex ELP1, HSF1, EMC1 ALOX5 1822/4885KDM4E 1938/4885LMNA 4405/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.