SCHEMBL4072228

SCHEMBL4072228

O=C1C=CC(=O)N1c1cccc2nc3ccccc3cc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR9 Q9NR96 2/20 0.50
ALDH1A1 P00352 4/20 0.49
KDM4E B2RXH2 2/20 0.49
GLA P06280 2/20 0.49
HPGD P15428 2/20 0.49
POLB P06746 2/20 0.49
NPC1 O15118 1/20 0.49
LMNA P02545 1/20 0.49
GAA P10253 1/20 0.49
PTBP1 P26599 1/20 0.49
RAB9A P51151 1/20 0.49
KMT2A Q03164 1/20 0.49
RCE1 Q9Y256 1/20 0.49
RXFP1 Q9HBX9 1/20 0.45
MGLL Q99685 12/20 0.45
MAPT P10636 1/20 0.44
ACHE P22303 1/20 0.44
HSP90AA1 P07900 3/20 0.41
PKM P14618 2/20 0.41
ATM Q13315 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30497722 1.00 TLR9 (0.50) TLR9ALDH1A1KDM4EGLAHPGD
SCHEMBL28171508 0.83 ALDH1A1 (0.47) ALDH1A1KDM4EGLAHPGDPOLB
SCHEMBL719837 0.80 TLR9 (0.57) TLR9ALDH1A1KDM4EHPGDPOLB
SCHEMBL31387987 0.80 TLR9 (0.57) TLR9ALDH1A1KDM4EHPGDPOLB
SCHEMBL28283393 0.79 KMT2A (0.56) ALDH1A1KDM4EGLAHPGDPOLB
SCHEMBL719069 0.78 TLR9 (0.55) TLR9ALDH1A1KDM4EHPGDPOLB
SCHEMBL723971 0.78 TLR9 (0.55) TLR9ALDH1A1KDM4EHPGDPOLB
SCHEMBL29386767 0.77 TLR9 (0.64) TLR9ALDH1A1HPGDPOLBMGLL
SCHEMBL152339 0.77 TLR9 (0.64) TLR9ALDH1A1HPGDPOLBMGLL
SCHEMBL28058868 0.76 KDM4E (0.47) ALDH1A1KDM4EGLAHPGDPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103360791-B Colorant dispersion 住友化学株式会社 2019-06-07 CN disclosed
CN-103365080-B Photosensitive composition 住友化学株式会社 2019-04-26 CN disclosed
US-20170327803-A1 HCV NS3 RECOMBINANT ANTIGENS AND MUTANTS THEREOF FOR IMPROVED ANTIBODY DETECTION ABBOTT LABORATORIES 2017-11-16 US disclosed
US-9790478-B2 HCV NS3 recombinant antigens and mutants thereof for improved antibody detection ABBOTT LABORATORIES (US) 2017-10-17 US disclosed
WO-2014143342-A9 HCV NS3 RECOMBINANT ANTIGENS AND MUTANTS THEREOF FOR IMPROVED ANTIBODY DETECTION ABBOTT LABORATORIES (US) 2017-05-18 WO disclosed
EP-2970947-A1 HCV NS3 RECOMBINANT ANTIGENS AND MUTANTS THEREOF FOR IMPROVED ANTIBODY DETECTION Abbott Laboratories (US) 2016-01-20 EP disclosed
CN-105209616-A HCV NS3 recombinant antigen and mutants thereof for improved antibody detection ABBOTT LAB 2015-12-30 CN disclosed
CN-102385251-B Radiation-sensitive resin composition, cured film, cured film forming method, color filter and color filter forming method JSR CORP 2015-04-01 CN disclosed
US-20140272932-A1 HCV NS3 RECOMBINANT ANTIGENS AND MUTANTS THEREOF FOR IMPROVED ANTIBODY DETECTION ABBOTT LABORATORIES (US) 2014-09-18 US disclosed
WO-2014143342-A1 HCV NS3 RECOMBINANT ANTIGENS AND MUTANTS THEREOF FOR IMPROVED ANTIBODY DETECTION ABBOTT LABORATORIES (US) 2014-09-18 WO disclosed
EP-0730152-B1 Regulating water treatment agent dosage based on operational system stresses NALCO CHEMICAL CO (US) 2002-09-18 EP disclosed
CN-1080882-C Regulating water treatment agent dosage based on operational system stresses NALCO CHEMICAL CO (US) 2002-03-13 CN disclosed
EP-1102782-A4 STRUCTURAL ANALOGS OF AMINE BASES AND NUCLEOSIDES BIO RAD LABORATORIES (US) 2002-01-30 EP disclosed
US-6335432-B1 FOR FLUORESCENT HYBRIDIZATION PROBES FOR USE IN DIAGNOSIS, RESEARCH, AND THERAPY BIO-RED LABORATORIES, INC. 2002-01-01 US disclosed
EP-1102782-A1 STRUCTURAL ANALOGS OF AMINE BASES AND NUCLEOSIDES Bio-Rad Laboratories (US) 2001-05-30 EP disclosed
WO-2000008041-A9 STRUCTURAL ANALOGS OF AMINE BASES AND NUCLEOSIDES BIO RAD LABORATORIES (US) 2001-02-01 WO disclosed
WO-2000008041-A1 STRUCTURAL ANALOGS OF AMINE BASES AND NUCLEOSIDES BIO-RAD LABORATORIES (US) 2000-02-17 WO disclosed
EP-0730152-A2 Regulating water treatment agent dosage based on operational system stresses NALCO CHEMICAL COMPANY (US) 1996-09-04 EP disclosed
CN-1113569-A Regulating water treatment agent dosage based on operational system stresses NALCO CHEMICAL CO (US) 1995-12-20 CN disclosed
US-5411889-A Regulating water treatment agent dosage based on operational system stresses NALCO CHEMICAL COMPANY (US) 1995-05-02 US disclosed