Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.47 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6024042 | 0.80 | HPGD (0.40) | KDM4EHPGDRAB9AALDH1A1KMT2A | |
| SCHEMBL28171508 | 0.78 | ALDH1A1 (0.47) | KDM4EHPGDRAB9AALDH1A1NPC1 | |
| SCHEMBL10941014 | 0.78 | POLB (0.52) | KDM4EHPGDALDH1A1NPC1KMT2A | |
| SCHEMBL28475699 | 0.77 | HPGD (0.46) | KDM4EHPGDRAB9AALDH1A1NPC1 | |
| SCHEMBL4072228 | 0.76 | TLR9 (0.50) | KDM4EHPGDRAB9AALDH1A1NPC1 | |
| SCHEMBL30497722 | 0.76 | TLR9 (0.50) | KDM4EHPGDRAB9AALDH1A1NPC1 | |
| SCHEMBL18493260 | 0.74 | KDM4E (0.50) | KDM4EHPGDRAB9AALDH1A1NPC1 | |
| SCHEMBL27873991 | 0.73 | NCF1 (0.55) | KDM4EHPGDRAB9AALDH1A1NPC1 | |
| SCHEMBL17954939 | 0.73 | MAPT (0.42) | KDM4EHPGDALDH1A1KMT2ALMNA | |
| SCHEMBL28283393 | 0.72 | KMT2A (0.56) | KDM4EHPGDRAB9AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105555279-A | Inhibition of MicroRNA for treatment of sepsis | LONDON HEALTH SCI CT RES INC | 2016-05-04 | — | — | CN | disclosed |