Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 6/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | NPC1L1 | Q9UHC9 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1002845 | 0.85 | AVPR1A (0.39) | AVPR1AUSP2SMN1; SMN2DDB1CRBN | |
| SCHEMBL4069310 | 0.81 | AVPR1A (0.39) | AVPR1AUSP2SMN1; SMN2DDB1CRBN | |
| SCHEMBL4067697 | 0.76 | CRBN (0.40) | AVPR1AUSP2SMN1; SMN2DDB1CRBN | |
| SCHEMBL4074130 | 0.76 | CRBN (0.39) | AVPR1AUSP2SMN1; SMN2DDB1CRBN | |
| SCHEMBL21843465 | 0.74 | USP2 (0.49) | AVPR1AUSP2SMN1; SMN2DDB1CRBN | |
| SCHEMBL14720194 | 0.74 | USP2 (0.40) | USP2SMN1; SMN2DDB1CRBNGPR119 | |
| SCHEMBL3495197 | 0.71 | USP2 (0.42) | USP2SMN1; SMN2DDB1CRBNNAMPT | |
| SCHEMBL10111390 | 0.70 | USP2 (0.41) | USP2SMN1; SMN2DDB1CRBNNAMPT | |
| SCHEMBL4072375 | 0.69 | AVPR1A (0.45) | AVPR1AUSP2SMN1; SMN2NAMPTGPR119 | |
| SCHEMBL17317373 | 0.68 | OPRM1 (0.45) | USP2SMN1; SMN2DDB1CRBNGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2072519-A1 | DIARYL KETIMINE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2009-06-24 | — | — | EP | disclosed |