SCHEMBL4072769

SCHEMBL4072769

C=Cc1cccc([Si](C)(C)C)c1[Si](C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.36
ALDH1A1 P00352 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methylamine SCHEMBL28005165 0.96 IDO1 (0.34) IDO1ALDH1A1
SCHEMBL4074799 0.81
SCHEMBL373961 0.80 ALDH1A1 (0.44) IDO1ALDH1A1
SCHEMBL3110894 0.77 IDO1 (0.41) IDO1
SCHEMBL8158012 0.73 ALDH1A1 (0.39) IDO1ALDH1A1
SCHEMBL17894148 0.73 IDO1 (0.33) IDO1ALDH1A1
SCHEMBL8158016 0.73 ATR (0.36) ALDH1A1
SCHEMBL17836940 0.73 NFE2L2 (0.44) ALDH1A1
SCHEMBL28553328 0.73 ALDH1A1 (0.31) ALDH1A1
SCHEMBL4071444 0.72 ALDH1A1 (0.33) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2019120-B1 BLOCK COPOLYMERS NIPPON SODA CO (JP) 2016-04-13 EP disclosed
US-8193285-B2 Block copolymers NIPPON SODA CO., LTD. (JP) 2012-06-05 US disclosed
US-20090253867-A1 BLOCK COPOLYMERS NIPPON SODA CO., LTD. (JP) 2009-10-08 US disclosed
EP-2019120-A1 BLOCK COPOLYMERS Nippon Soda Co., Ltd. (JP) 2009-01-28 EP disclosed
EP-0008997-B1 THERMOPLASTIC POLYSTYRENE-DIORGANOPOLYSILOXANE ELASTOMERS AND PROCESS FOR THE MANUFACTURE THEREOF RHONE-POULENC INDUSTRIES (FR) 1981-06-17 EP disclosed
US-4263401-A Thermoplastic, elastomeric polystyrene/diorganopolysiloxane block copolymers RHONE-POULENC INDUSTRIES (FR) 1981-04-21 US disclosed
EP-0008997-A2 Thermoplastic polystyrene-diorganopolysiloxane elastomers and process for the manufacture thereof RHONE-POULENC INDUSTRIES (FR) 1980-03-19 EP disclosed