Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3 | P56703 | 1/20 | 0.45 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12788624 | 0.81 | HSD17B10 (0.46) | HSD17B10 | |
| SCHEMBL3612934 | 0.78 | — | — | |
| SCHEMBL13873135 | 0.77 | ALDH1A1 (0.53) | LMNAHSD17B10 | |
| SCHEMBL3174166 | 0.77 | LMNA (0.55) | LMNAHSD17B10 | |
| SCHEMBL4898833 | 0.77 | LMNA (0.55) | LMNAHSD17B10 | |
| SCHEMBL4019094 | 0.76 | HPGD (0.50) | — | |
| SCHEMBL5520943 | 0.76 | HSD17B10 (0.45) | HSD17B10 | |
| SCHEMBL13887670 | 0.76 | HSD17B10 (0.50) | HSD17B10 | |
| SCHEMBL22455535 | 0.76 | F2 (0.49) | LMNAHSD17B10 | |
| SCHEMBL7680329 | 0.76 | LMNA (0.44) | WNT3SFRP1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038041-A2 | THERAPEUTIC COMPOUNDS AND THEIR USE IN CANCER | Myriad Genetics, Inc. (US) | 2009-03-25 | — | — | EP | disclosed |
| WO-2007134298-A2 | THERAPEUTIC COMPOUNDS AND THEIR USE IN CANCER | MYRIAD GENETICS, INC. (US) | 2007-11-22 | — | — | WO | disclosed |