Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
| ▸ | TDP2 | O95551 | 1/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | GALK1 | P51570 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6525291 | 0.82 | CYP2C19 (0.39) | MEN1KMT2AKDM4EMAPTCYP2C19 | |
| SCHEMBL20640547 | 0.82 | CA2 (0.34) | ATMKMT2AMAPTL3MBTL1RIPK1 | |
| SCHEMBL1739510 | 0.80 | GSR (0.44) | ATMBLML3MBTL1RIPK1TRPA1 | |
| SCHEMBL14984000 | 0.80 | GSR (0.44) | ATMBLML3MBTL1RIPK1TRPA1 | |
| SCHEMBL8405099 | 0.80 | GSR (0.44) | ATMBLML3MBTL1RIPK1TRPA1 | |
| SCHEMBL6525612 | 0.78 | ATM (0.39) | ATMMEN1KMT2AKDM4EMAPT | |
| SCHEMBL3361796 | 0.77 | KDM4E (0.38) | ATMMEN1KMT2AKDM4EAPAF1 | |
| SCHEMBL3386536 | 0.76 | TAAR1 (0.41) | AOC3CA2 | |
| SCHEMBL3386535 | 0.76 | TAAR1 (0.41) | AOC3CA2 | |
| SCHEMBL3386613 | 0.76 | TAAR1 (0.41) | AOC3CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102438619-A | Isoprenylated bisphosphonates as antituberculosis agents | UNIV IOWA RES FOUND | 2012-05-02 | — | — | CN | disclosed |
| EP-2408447-A1 | PRENYLATED BISPHOSPHONATES AS ANTI-TUBERCULOSIS AGENTS | University of Iowa Research Foundation (US) | 2012-01-25 | — | — | EP | disclosed |
| WO-2010108190-A1 | PRENYLATED BISPHOSPHONATES AS ANTI-TUBERCULOSIS AGENTS | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2010-09-23 | — | — | WO | disclosed |