Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
| ▸ | FABP3 | P05413 | 1/20 | 0.30 |
| ▸ | FABP4 | P15090 | 1/20 | 0.30 |
| ▸ | PRNP | P04156 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4746949 | 0.78 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2MAPK1HTTCYP3A4 | |
| SCHEMBL5391695 | 0.69 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2MAPK1HTTCYP3A4 | |
| SCHEMBL31125623 | 0.69 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2MAPK1HTTCYP3A4 | |
| SCHEMBL7788152 | 0.69 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2MAPK1HTTCYP3A4 | |
| SCHEMBL22445800 | 0.68 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2MAPK1HTTCYP3A4 | |
| SCHEMBL3758654 | 0.66 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2MAPK1HTTCYP3A4 | |
| SCHEMBL2132960 | 0.66 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2MAPK1HTTCYP3A4 | |
| Hydrochloric Acid SCHEMBL4244328 | 0.65 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2MAPK1HTTCYP3A4 | |
| Hydrochloric Acid SCHEMBL3758009 | 0.65 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2MAPK1HTTCYP3A4 | |
| SCHEMBL21826149 | 0.64 | POLB (0.56) | ALDH1A1SMN1; SMN2MAPK1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1942890-A4 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORP (US) | 2009-08-26 | — | — | EP | disclosed |
| EP-1942890-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC. (CA) | 2008-07-16 | — | — | EP | disclosed |
| WO-2006138350-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC. (CA) | 2006-12-28 | — | — | WO | disclosed |