Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 1/20 | 0.53 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.53 |
| ▸ | PARP10 | Q53GL7 | 7/20 | 0.50 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.46 |
| ▸ | PARP4 | Q9UKK3 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.45 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.45 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.45 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29222811 | 0.88 | PLA2G10 (0.50) | PLA2G10PLA2G2APARP10CYP17A1PARP4 | |
| SCHEMBL27961330 | 0.82 | TDP1 (0.48) | ALDH1A1KMT2ATDP1POLBMAPT | |
| SCHEMBL11612824 | 0.82 | TDP1 (0.48) | ALDH1A1KMT2ATDP1POLBCYP2C19 | |
| SCHEMBL61340 | 0.82 | CES2 (0.57) | PLA2G10PLA2G2APARP10CYP17A1PARP4 | |
| SCHEMBL2633786 | 0.80 | PLA2G10 (0.55) | PLA2G10PLA2G2APARP10CYP17A1PARP4 | |
| Hydrochloric Acid SCHEMBL15021131 | 0.80 | CES2 (0.55) | PLA2G10PLA2G2APARP10CYP17A1PARP4 | |
| SCHEMBL8867699 | 0.80 | PLA2G10 (0.55) | PLA2G10PLA2G2APARP10CYP17A1PARP4 | |
| SCHEMBL83677 | 0.80 | ALDH1A1 (0.56) | ALDH1A1KMT2ATDP1POLBMAPT | |
| SCHEMBL2861358 | 0.80 | PLA2G10 (0.55) | PLA2G10PLA2G2APARP10CYP17A1PARP4 | |
| SCHEMBL5536952 | 0.78 | PLA2G10 (0.53) | PLA2G10PLA2G2APARP10CYP17A1PARP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105073742-A | Flap modulators | JANSSEN PHARMACEUTICA NV | 2015-11-18 | — | — | CN | disclosed |
| CN-105001226-A | Tricycle heterocyclic compounds and JAK inhibitors | NISSAN CHEMICAL IND LTD | 2015-10-28 | — | — | CN | disclosed |
| CN-104487433-A | Triazolone compounds as mpges-1 inhibitors | GLENMARK PHARMACEUTICALS SA | 2015-04-01 | — | — | CN | disclosed |
| CN-103889976-A | Indazole compounds, compositions and methods of use | HOFFMANN LA ROCHE | 2014-06-25 | — | — | CN | disclosed |
| CN-103732597-A | Tricyclic heterocyclic compounds and JAK inhibitors | NISSAN CHEMICAL IND LTD | 2014-04-16 | — | — | CN | disclosed |
| CN-101035765-B | Sulfonamide derivatives | HOFFMANN LA ROCHE | 2010-10-13 | — | — | CN | disclosed |
| CN-101747324-A | Sulfonamide derivatives | HOFFMANN LA ROCHE | 2010-06-23 | — | — | CN | disclosed |
| US-7488748-B2 | 3,6-Disubstituted azabicyclo hexane derivatives as muscarinic receptor antagonists | RANBAXY LABORATORIES LIMITED (IN) | 2009-02-10 | — | — | US | disclosed |
| CN-101035765-A | Sulfonamide derivatives | HOFFMANN LA ROCHE (CH) | 2007-09-12 | — | — | CN | disclosed |
| CN-101031541-A | 4-aminomethyl benzamidine derivatives and their use as factor VIIIa inhibitors | HOFFMANN LA ROCHE (CH) | 2007-09-05 | — | — | CN | disclosed |
| EP-0505376-B1 | MUSCARINIC RECEPTOR ANTAGONISTS | PFIZER LTD (GB) | 1994-12-07 | — | — | EP | disclosed |
| US-5340831-A | Muscarinic receptor antagonists | PFIZER INC. (US) | 1994-08-23 | — | — | US | disclosed |
| EP-0505376-A1 | MUSCARINIC RECEPTOR ANTAGONISTS. | PFIZER LTD (GB) | 1992-09-30 | — | — | EP | disclosed |
| EP-0441852-A1 | MUSCARINIC RECEPTOR ANTAGONISTS. | PFIZER LTD (GB) | 1991-08-21 | — | — | EP | disclosed |
| CN-1052672-A | Benzofuran derivative | GLAXO GROUP LTD (GB) | 1991-07-03 | — | — | CN | disclosed |
| WO-1991009013-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | PFIZER LIMITED (GB) | 1991-06-27 | — | — | WO | disclosed |
| EP-0376358-A1 | Muscarinic receptor antagonists | PFIZER INC. (US) | 1990-07-04 | — | — | EP | disclosed |
| WO-1990005133-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | PFIZER LIMITED (GB) | 1990-05-17 | — | — | WO | disclosed |
| CN-1041583-A | MUSCARMIC RECEPTOR ANTAGONISTS | PFIZER (US) | 1990-04-25 | — | — | CN | disclosed |
| CN-1033627-A | New-N-[1-(thienyl) ethyl] sulfonamide derivatives and contain the weedicide that this compound is an effective ingredient | DAIKIN INUDSTRIES LTD (JP) | 1989-07-05 | — | — | CN | disclosed |