Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.61 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4074161 | 0.80 | SIGMAR1 (0.67) | SIGMAR1OPRM1OPRD1OPRK1 | |
| SCHEMBL4077581 | 0.76 | SIGMAR1 (0.51) | SIGMAR1 | |
| SCHEMBL4072644 | 0.75 | SIGMAR1 (0.74) | SIGMAR1OPRM1OPRD1OPRK1 | |
| SCHEMBL4315635 | 0.75 | SIGMAR1 (0.59) | SIGMAR1 | |
| SCHEMBL4066653 | 0.74 | SIGMAR1 (0.62) | SIGMAR1OPRM1OPRD1OPRK1 | |
| SCHEMBL3403111 | 0.64 | SIGMAR1 (0.72) | SIGMAR1OPRM1OPRD1OPRK1 | |
| SCHEMBL2360466 | 0.64 | SIGMAR1 (0.72) | SIGMAR1OPRM1OPRD1OPRK1 | |
| SCHEMBL2360468 | 0.64 | SIGMAR1 (0.72) | SIGMAR1OPRM1OPRD1OPRK1 | |
| SCHEMBL25358883 | 0.64 | SIGMAR1 (0.74) | SIGMAR1OPRM1OPRD1OPRK1 | |
| SCHEMBL1966477 | 0.63 | SIGMAR1 (0.61) | SIGMAR1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090247560-A1 | Diaryl ketimine derivative | BANYU PHARMACEUTICAL CO., LTD. | 2009-10-01 | — | — | US | disclosed |
| EP-2072519-A1 | DIARYL KETIMINE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2009-06-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247560-A1 | Diaryl ketimine derivative | NR0B2, NR2C2, NR3C2 | SIGMAR1 1623/4885OPRM1 1328/4885OPRD1 808/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.