Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11917839 | 0.87 | MAPK1 (0.44) | POLBKDM4EMAPTL3MBTL1KMT2A | |
| SCHEMBL13829103 | 0.86 | L3MBTL1 (0.44) | POLBKDM4EL3MBTL1KMT2AALDH1A1 | |
| SCHEMBL18113163 | 0.84 | POLB (0.49) | POLBKDM4EMAPTL3MBTL1KMT2A | |
| SCHEMBL20425676 | 0.84 | AKT1 (0.48) | POLBKDM4EMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL4231270 | 0.84 | MAPT (0.49) | POLBMAPTL3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL18113132 | 0.83 | CYP4F2 (0.49) | POLBMAPTL3MBTL1KMT2ACYP4F2 | |
| SCHEMBL18496979 | 0.79 | CYP1A2 (0.48) | MAPTL3MBTL1SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL4437686 | 0.78 | ALDH1A1 (0.43) | MAPTKMT2ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL24450191 | 0.78 | CYP2D6 (0.36) | POLBKDM4EMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL18113261 | 0.76 | ALDH1A1 (0.50) | POLBKDM4EMAPTL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3277736-B1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA SRL (IT) | 2019-03-27 | — | — | EP | disclosed |
| US-10011668-B2 | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2018-07-03 | — | — | US | disclosed |
| US-20180057622-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2018-03-01 | — | — | US | disclosed |
| EP-3277736-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.r.l. (IT) | 2018-02-07 | — | — | EP | disclosed |
| WO-2016156473-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2016-10-06 | — | — | WO | disclosed |
| WO-2009046016-A1 | FLUOROPOLYMER | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-04-09 | — | — | WO | disclosed |