SCHEMBL407343

SCHEMBL407343

Cc1ccc2c(c1)N=N[N]2

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO2 P16083 1/20 0.37
CYP1A2 P05177 4/20 0.36
CYP2A6 P11509 3/20 0.36
SMN1; SMN2 Q16637 2/20 0.33
GAA P10253 1/20 0.33
HTT P42858 1/20 0.33
TDP1 Q9NUW8 6/20 0.32
TP53 P04637 2/20 0.32
CYP3A4 P08684 1/20 0.32
THRB P10828 1/20 0.32
ALOX15 P16050 1/20 0.32
TRPA1 O75762 1/20 0.32
ACHE P22303 3/20 0.32
KDM4E B2RXH2 2/20 0.31
MAPT P10636 2/20 0.31
UHRF1 Q96T88 1/20 0.31
ALDH1A1 P00352 1/20 0.31
CCR1 P32246 1/20 0.31
CCR5 P51681 1/20 0.31
CCR8 P51685 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10469300 0.91 NQO2 (0.37) NQO2CYP1A2CYP2A6SMN1; SMN2GAA
SCHEMBL1387779 0.72 NQO2 (0.33) NQO2
SCHEMBL4671502 0.71 TP53 (0.35) CYP2A6SMN1; SMN2TDP1TP53CYP3A4
SCHEMBL10467387 0.71 ALDH1A1 (0.42) NQO2CYP1A2CYP2A6SMN1; SMN2CYP3A4
SCHEMBL7449167 0.62 CYP1A2 (0.36) NQO2CYP1A2CYP2A6SMN1; SMN2GAA
SCHEMBL8650493 0.62 CYP2A6 (0.32) CYP2A6TDP1ALOX15ALDH1A1NOS3
SCHEMBL23537533 0.62 CYP1A2 (0.41) NQO2CYP1A2CYP2A6SMN1; SMN2TDP1
SCHEMBL10469489 0.62 MAPK13 (0.31)
SCHEMBL2961402 0.62 CYP1A2 (0.41) NQO2CYP1A2CYP2A6SMN1; SMN2GAA
SCHEMBL24891183 0.60 CYP1A2 (0.35) NQO2CYP1A2CYP2A6SMN1; SMN2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4927734-A CONTAINING A FORMYLHYDRAZINOPYRIDINE COMPOUND DAINIPPON INK. AND CHEMICALS, INC. (JP) 1990-05-22 US claimed
EP-0322553-A1 Silver halide photographic light-sensitive material and a process for forming a high contrastphotographic image DAINIPPON INK AND CHEMICALS, INC. (JP) 1989-07-05 EP claimed
CN-106588892-B Coumarin derived fluconazole analogue and preparation method and application thereof 西南大学 2021-11-02 CN disclosed
CN-106588955-B Fluconazole analogue derived from imidazobenzothiazole, and preparation method and application thereof 西南大学 2020-08-18 CN disclosed
US-8361627-B2 Anti-corrosion layer for aluminum and magnesium alloys EADS DEUTSCHLAND GMBH (DE) 2013-01-29 US disclosed
US-20120021232-A1 ANTI-CORROSION LAYER FOR ALUMINUM AND MAGNESIUM ALLOYS TECHNISCHE UNIVERSITÄT WIEN (AT) 2012-01-26 US disclosed
EP-2379623-A1 ANTI-CORROSION LAYER FOR ALUMINUM AND MAGNESIUM ALLOYS EADS Deutschland GmbH (DE) 2011-10-26 EP disclosed
WO-2010081757-A1 ANTI-CORROSION LAYER FOR ALUMINUM AND MAGNESIUM ALLOYS EADS DEUTSCHLAND GMBH (DE) 2010-07-22 WO disclosed
US-5202225-A High speed, high efficiency FUJI PHOTO FILM CO., LTD. (JP) 1993-04-13 US disclosed
US-5142029-A Redox system FUJI PHOTO FILM CO., LTD. (JP) 1992-08-25 US disclosed
US-4950764-A HERBICIDES, BACTERICIDES, ANALGESICS, ANTIINFLAMMATORY AGENT FUJI PHOTO FILM CO., LTD. (JP) 1990-08-21 US disclosed
EP-0167168-B1 SILVER HALIDE PHOTOGRAPHIC MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1989-11-15 EP disclosed
EP-0198438-B1 SILVER HALIDE PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1989-10-18 EP disclosed
US-4770990-A Silver halide photographic light-sensitive material containing a compound capable of imagewise releasing a photographically useful group during development FUJI PHOTO FILM CO., LTD. (JP) 1988-09-13 US disclosed
US-4740453-A Silver halide photosensitive material containing a compound capable of releasing a photographically useful group FUJI PHOTO FILM CO., LTD. (JP) 1988-04-26 US disclosed
EP-0198438-A2 Silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1986-10-22 EP disclosed
EP-0167168-A2 Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1986-01-08 EP disclosed
US-4242507-A Sulfonic acid esters FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1980-12-30 US disclosed