Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.70 |
| ▸ | CHKA | P35790 | 1/20 | 0.70 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.48 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.48 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.48 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9396214 | 0.92 | CA2 (0.59) | CA2CHKACA12CA1CA9 | |
| SCHEMBL937637 | 0.84 | CA2 (0.95) | CA2CHKACA12CA1CA9 | |
| SCHEMBL8288869 | 0.83 | ALDH1A1 (0.56) | CA2CHKACA12CA1CA9 | |
| SCHEMBL3175235 | 0.82 | CA2 (1.00) | CA2CHKACA12CA1CA9 | |
| Hydrochloric Acid SCHEMBL23124310 | 0.82 | CA2 (0.91) | CA2CHKACA12CA1CA9 | |
| SCHEMBL3821587 | 0.81 | CA2 (0.54) | CA2CHKACA12CA1CA9 | |
| Hydrochloric Acid SCHEMBL30493400 | 0.80 | CA2 (0.95) | CA2CHKACA12CA1CA9 | |
| SCHEMBL8024247 | 0.80 | ALDH1A1 (0.61) | CA2CHKACA12CA1CA9 | |
| SCHEMBL4261207 | 0.80 | ALDH1A1 (0.61) | CA2CHKACA12CA1CA9 | |
| SCHEMBL11889662 | 0.80 | ALDH1A1 (0.58) | CA2CHKACA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2065053-A1 | CELL DEATH INHIBITOR | Takeda Pharmaceutical Company Limited (JP) | 2009-06-03 | — | — | EP | disclosed |
| EP-1897880-A1 | 1,3-BENZOTHIAZINONE DERIVATIVE AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2008-03-12 | — | — | EP | disclosed |