Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.48 |
| ▸ | ME3 | Q16798 | 1/20 | 0.48 |
| ▸ | AOC2 | O75106 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.45 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | KDM5A | P29375 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | DEGS1 | O15121 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28184738 | 0.86 | SMN1; SMN2 (0.48) | ME3KDM4EUSP2 | |
| SCHEMBL3085835 | 0.84 | AOC2 (0.59) | SMYD3AOC2HDAC6KDM4EUSP2 | |
| SCHEMBL30476653 | 0.80 | HDAC6 (0.71) | SMYD3AOC2HDAC6KDM4EUSP2 | |
| SCHEMBL1164809 | 0.79 | CHRM4 (0.53) | ME3KDM4E | |
| Hydrochloric Acid SCHEMBL25319983 | 0.79 | HDAC6 (0.69) | SMYD3AOC2HDAC6KDM4EUSP2 | |
| SCHEMBL7337653 | 0.79 | HDAC6 (0.69) | SMYD3AOC2HDAC6KDM4EUSP2 | |
| SCHEMBL15056065 | 0.78 | MAPT (0.67) | — | |
| SCHEMBL13558242 | 0.78 | USP2 (0.55) | SMYD3AOC2HDAC6KDM4EUSP2 | |
| SCHEMBL12524169 | 0.78 | HDAC6 (0.61) | AOC2HDAC6KDM4EHDAC3HDAC8 | |
| SCHEMBL6134717 | 0.77 | ITGB3 (0.52) | SMYD3HDAC6KDM4EHDAC3HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009155362-A1 | SMALL MOLECULE HEMATOPOIETIC GROWTH FACTOR MIMETIC COMPOUNDS AND THEIR USES | LIGAND PHARMACEUTICALS INC. (US) | 2009-12-23 | — | — | WO | disclosed |