Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 9/20 | 0.73 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 3/20 | 0.31 |
| ▸ | MAOB | P27338 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10854575 | 0.96 | NISCH (0.73) | NISCHNOS3NOS1NOS2CYP2D6 | |
| SCHEMBL10852808 | 0.94 | NISCH (0.77) | NISCHNOS3NOS1NOS2CYP2D6 | |
| SCHEMBL574072 | 0.93 | NISCH (0.69) | NISCHNOS3NOS1NOS2CYP2D6 | |
| SCHEMBL21391659 | 0.86 | NISCH (0.95) | NISCHCYP2D6HTR1AADRA2AADRA1A | |
| SCHEMBL19348515 | 0.84 | — | — | |
| SCHEMBL11130232 | 0.84 | NISCH (0.91) | NISCHCYP2D6HTR1AADRA2AADRA1A | |
| SCHEMBL1139763 | 0.84 | NISCH (1.00) | NISCHCYP2D6HTR1AADRA2AADRA1A | |
| SCHEMBL8142116 | 0.84 | NISCH (1.00) | NISCHCYP2D6HTR1AADRA2AADRA1A | |
| SCHEMBL11132739 | 0.82 | NISCH (0.87) | NISCHCYP2D6HTR1AADRA2AADRA1A | |
| SCHEMBL11132717 | 0.80 | NISCH (0.83) | NISCHCYP2D6HTR1AADRA2AADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090082588-A1 | Process for producing fluorinated carbamates and isocyanates | REPSOL YPF, S.A. (ES) | 2009-03-26 | — | — | US | claimed |
| EP-2036884-A1 | Process for producing fluorinated isocyanates and carbamates | REPSOL YPF S.A. (ES) | 2009-03-18 | — | — | EP | claimed |
| CN-107074821-A | It is used as the diamines macrocyclic compound of FXIA inhibitor | 百时美施贵宝公司 | 2017-08-18 | — | — | CN | disclosed |
| US-20090082588-A1 | Process for producing fluorinated carbamates and isocyanates | REPSOL YPF, S.A. (ES) | 2009-03-26 | — | — | US | disclosed |
| EP-2036884-A1 | Process for producing fluorinated isocyanates and carbamates | REPSOL YPF S.A. (ES) | 2009-03-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090082588-A1 | Process for producing fluorinated carbamates and isocyanates | SRM, CA4, PRMT3 | NISCH 27/4885NOS3 167/4885NOS1 244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.