Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | CAD | P27708 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.31 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.31 |
| ▸ | ITGAV | P06756 | 1/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.31 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.31 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.31 |
| ▸ | ITGAL | P20701 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4073276 | 0.64 | L3MBTL1 (0.33) | HSD17B10CADITGB3ITGB2ITGB1 | |
| SCHEMBL1744829 | 0.62 | MEN1 (0.30) | — | |
| SCHEMBL29134462 | 0.61 | — | — | |
| SCHEMBL27626627 | 0.61 | — | — | |
| SCHEMBL5988758 | 0.61 | — | — | |
| SCHEMBL4968607 | 0.60 | ITGB1 (0.37) | HSD17B10ITGB3ITGB2ITGB1ITGAV | |
| SCHEMBL2879208 | 0.60 | ALDH1A1 (0.51) | HSD17B10ALDH1A1POLBBLM | |
| SCHEMBL23802896 | 0.59 | KDM4E (0.30) | HSD17B10ALDH1A1POLBBLM | |
| SCHEMBL23802780 | 0.59 | KDM4E (0.30) | HSD17B10ALDH1A1POLBBLM | |
| SCHEMBL4751144 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009049018-A1 | NOVEL COMPOUNDS AND METHODS OF USING THEM | SYNDAX PHARMACEUTICALS, INC. (US) | 2009-04-16 | — | — | WO | disclosed |