SCHEMBL4074960

SCHEMBL4074960

C=C(C)C(=O)OCCOCCOCCOCCOC(=O)c1ccc(O)c(O)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.55
CA1 P00915 3/20 0.55
CA2 P00918 3/20 0.55
CA7 P43166 3/20 0.55
CA9 Q16790 3/20 0.55
CA14 Q9ULX7 3/20 0.55
SERPINE1 P05121 4/20 0.53
PTPN1 P18031 1/20 0.51
THRB P10828 1/20 0.47
XDH P47989 1/20 0.47
ESR1 P03372 3/20 0.46
ESR2 Q92731 1/20 0.46
KDM4E B2RXH2 2/20 0.45
POLB P06746 2/20 0.45
HDAC6 Q9UBN7 1/20 0.45
GAA P10253 1/20 0.44
PKM P14618 1/20 0.44
APEX1 P27695 1/20 0.43
HTT P42858 1/20 0.43
TDP1 Q9NUW8 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL838089 0.96 CA12 (0.59) CA12CA1CA2CA7CA9
SCHEMBL6880500 0.89 HDAC6 (0.58) CA12CA1CA2CA7CA9
SCHEMBL26112490 0.89 HDAC6 (0.58) CA12CA1CA2CA7CA9
SCHEMBL9546478 0.88 SERPINE1 (0.46) CA12CA1CA2CA7CA9
SCHEMBL12394960 0.86 SERPINE1 (0.73) SERPINE1THRBESR1TYRL3MBTL1
SCHEMBL12394962 0.86 SERPINE1 (0.73) SERPINE1THRBESR1TYRL3MBTL1
SCHEMBL13567308 0.84 CA1 (0.49) CA12CA1CA2CA7CA9
SCHEMBL17034393 0.84 ESR1 (0.57) CA12CA1CA2CA7CA9
SCHEMBL18906123 0.83 POLB (0.46) CA12CA1CA2CA7CA9
SCHEMBL4640172 0.83 POLB (0.45) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140224140-A1 PRINTING METHOD USING LITHOGRAPHIC PRINTING PLATE PRECURSOR OF ON-PRESS DEVELOPMENT TYPE FUJIFILM COPORATION (JP) 2014-08-14 US disclosed
US-20120295204-A1 PROCESSING METHOD OF LITHOGRAPHIC PRINTING PLATE PREURSOR FUJIFILM CORPORATION (JP) 2012-11-22 US disclosed
US-20120227605-A1 ALUMINUM ALLOY PLATE FOR LITHOGRAPHIC PRINTING PLATE, LITHOGRAPHIC PRINTING PLATE SUPPORT, PRESENSITIZED PLATE, METHOD OF MANUFACTURING ALUMINUM ALLOY PLATE FOR LITHOGRAPHIC PRINTING PLATE AND METHOD OF MANUFACTURING LITHOGRAPHIC PRINTING PLATE SUPPORT FUJIFILM CORPORATION (JP) 2012-09-13 US disclosed
US-20120103220-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR SONOKAWA KOJI (JP) 2012-05-03 US disclosed
US-20110168044-A1 METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2011-07-14 US disclosed
US-20110159437-A1 METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2011-06-30 US disclosed
US-20110134411-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR, LITHOGRAPHIC PRINTING METHOD AND PACKAGED BODY OF LITHOGRAPHIC PRINTING PLATE PRECURSORS MITSUMOTO TOMOYOSHI 2011-06-09 US disclosed
US-7939240-B2 Lithographic printing plate precursor and method of producing printing plate FUJIFILM CORPORATION (JP) 2011-05-10 US disclosed
US-20110091814-A1 PROCESS FOR MAKING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2011-04-21 US disclosed
US-20110054212-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING PROCESS OOHASHI HIDEKAZU 2011-03-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110054212-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING PROCESS FLNA, PFN1, FLNB CA12 1720/4885CA1 852/4885CA2 1584/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.