Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4074981 | 1.00 | MAPT (0.38) | MAPTHSD17B10ALDH1A1ADRA2AADRA2B | |
| SCHEMBL21715832 | 1.00 | MAPT (0.38) | MAPTHSD17B10ALDH1A1ADRA2AADRA2B | |
| SCHEMBL3968881 | 0.85 | HSD17B10 (0.44) | MAPTHSD17B10ALDH1A1ADRA2AADRA2B | |
| SCHEMBL3968879 | 0.85 | HSD17B10 (0.44) | MAPTHSD17B10ALDH1A1ADRA2AADRA2B | |
| SCHEMBL9976117 | 0.85 | HSD17B10 (0.44) | MAPTHSD17B10ALDH1A1ADRA2AADRA2B | |
| SCHEMBL31493860 | 0.85 | HSD17B10 (0.44) | MAPTHSD17B10ALDH1A1ADRA2AADRA2B | |
| SCHEMBL4402093 | 0.84 | HSD17B10 (0.43) | MAPTHSD17B10ALDH1A1ADRA2AADRA2B | |
| SCHEMBL4402096 | 0.84 | HSD17B10 (0.43) | MAPTHSD17B10ALDH1A1ADRA2AADRA2B | |
| SCHEMBL4405611 | 0.84 | HSD17B10 (0.43) | MAPTHSD17B10ALDH1A1ADRA2AADRA2B | |
| SCHEMBL4405615 | 0.84 | HSD17B10 (0.43) | MAPTHSD17B10ALDH1A1ADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090243468-A1 | ARYLIMINO-ISOINDOLINE COMPLEXES FOR USE IN ORGANIC LIGHT EMITTING DIODES | THE UNIVERSITY OF SOUTHERN CALIFORNIA | 2009-10-01 | — | — | US | disclosed |
| WO-2009052268-A1 | ARYLIMINO-ISOINDOLINE COMPLEXES FOR USE IN ORGANIC LIGHT EMITTING DIODES | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2009-04-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090243468-A1 | ARYLIMINO-ISOINDOLINE COMPLEXES FOR USE IN ORGANIC LIGHT EMITTING DIODES | BRI3BP, PPOX, MAP1LC3C | MAPT 288/4885HSD17B10 4209/4885ALDH1A1 486/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.