Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9831062 | 0.86 | HTT (0.44) | TSHRHTTKMOPLK1ALDH1A1 | |
| Flumioxazin SCHEMBL29539500 | 0.82 | GRM1 (0.37) | — | |
| Flumioxazin SCHEMBL39699 | 0.82 | GRM1 (0.37) | — | |
| Flumioxazin SCHEMBL29088353 | 0.81 | GRM1 (0.37) | — | |
| Flumioxazin SCHEMBL2231264 | 0.79 | — | — | |
| SCHEMBL10504486 | 0.79 | TSHR (0.41) | TSHRHTTALDH1A1 | |
| SCHEMBL10879051 | 0.79 | KMO (0.35) | TSHRHTTKMOPLK1ALDH1A1 | |
| Flumioxazin SCHEMBL19641848 | 0.78 | GRM1 (0.39) | — | |
| SCHEMBL9687032 | 0.78 | BRD4 (0.36) | TSHRHTTKMO | |
| SCHEMBL9423272 | 0.78 | SLC5A1 (0.38) | TSHRHTTKMOPLK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0170191-B1 | TETRAHYDROPHTALIMIDES, AND THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-11-23 | — | — | EP | claimed |
| US-4640707-A | Tetrahydrophthalimides and their herbicidal use | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1987-02-03 | — | — | US | claimed |
| EP-0170191-A2 | Tetrahydrophtalimides, and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-02-05 | — | — | EP | claimed |
| US-7586023-B1 | Methods of conferring ppo-inhibiting herbicide resistance to plants by gene manipulation | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-09-08 | — | — | US | disclosed |
| EP-0839193-B1 | PORPHYRIN-ACCUMULATING TYPE HERBICIDE RESISTANCE GENE | SUMITOMO CHEMICAL CO (JP) | 2006-12-20 | — | — | EP | disclosed |
| US-6160206-A | Porphyrin-accumulating type herbicide resistance gene | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2000-12-12 | — | — | US | disclosed |
| EP-0170191-B1 | TETRAHYDROPHTALIMIDES, AND THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-11-23 | — | — | EP | disclosed |
| US-4880925-A | HERBICIDES | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1989-11-14 | — | — | US | disclosed |
| US-4792605-A | TETRAHYDROPHTHALIMIDES; HERBICIDES | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1988-12-20 | — | — | US | disclosed |
| US-4640707-A | Tetrahydrophthalimides and their herbicidal use | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1987-02-03 | — | — | US | disclosed |
| EP-0170191-A2 | Tetrahydrophtalimides, and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-02-05 | — | — | EP | disclosed |