Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | SLC5A1 | P13866 | 4/20 | 0.36 |
| ▸ | SLC5A2 | P31639 | 4/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KMO | O15229 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9686613 | 0.87 | BRD4 (0.43) | BRD4SLC5A1SLC5A2PIK3CGTSHR | |
| SCHEMBL9686487 | 0.86 | CYP1B1 (0.36) | CYP1B1 | |
| SCHEMBL9687661 | 0.84 | BRD4 (0.54) | BRD4PIK3CGTSHRL3MBTL1 | |
| SCHEMBL9687722 | 0.80 | HDAC4 (0.39) | BRD4SLC5A1SLC5A2PIK3CGTSHR | |
| SCHEMBL4075188 | 0.78 | TSHR (0.38) | TSHRHTTKMO | |
| SCHEMBL9423272 | 0.75 | SLC5A1 (0.38) | BRD4SLC5A1SLC5A2TSHRHTT | |
| SCHEMBL9872261 | 0.72 | NMT1 (0.37) | BRD4PIK3CGTSHRHTTCYP1B1 | |
| SCHEMBL9686626 | 0.69 | HDAC4 (0.41) | BRD4SLC5A1SLC5A2PIK3CGTSHR | |
| SCHEMBL9685904 | 0.69 | BRD4 (0.49) | BRD4TSHR | |
| SCHEMBL9687072 | 0.67 | CYP1B1 (0.35) | BRD4CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0296416-B1 | BENZO-ANELLATED CYCLIC COMPOUNDS | NIHON BAYER AGROCHEM K.K. (JP) | 1992-07-29 | — | — | EP | disclosed |
| US-5077401-A | Herbicides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1991-12-31 | — | — | US | disclosed |
| US-4902335-A | Benzo-fused cyclic compounds | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1990-02-20 | — | — | US | disclosed |
| EP-0296416-A1 | Benzo-anellated cyclic compounds | NIHON BAYER AGROCHEM K.K. (JP) | 1988-12-28 | — | — | EP | disclosed |