Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | OXER1 | Q8TDS5 | 3/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 2/20 | 0.33 |
| ▸ | CDC25A | P30304 | 6/20 | 0.33 |
| ▸ | CDC25B | P30305 | 6/20 | 0.33 |
| ▸ | CDC25C | P30307 | 5/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17669647 | 0.87 | AKR1B1 (0.38) | AKR1B1PRKCASCDALDH1A1TSHR | |
| SCHEMBL23533422 | 0.78 | GPR84 (0.45) | OXER1AKR1B1ALDH1A1TSHRSLC22A6 | |
| SCHEMBL11838734 | 0.78 | GPR84 (0.45) | OXER1AKR1B1ALDH1A1TSHRSLC22A6 | |
| SCHEMBL11829345 | 0.78 | GPR84 (0.45) | OXER1AKR1B1ALDH1A1TSHRSLC22A6 | |
| SCHEMBL9360186 | 0.77 | SIRT2 (0.40) | SIRT2 | |
| SCHEMBL244829 | 0.76 | TSHR (0.50) | AKR1B1ALDH1A1TSHRSLC22A6SLC22A8 | |
| SCHEMBL20073868 | 0.76 | SIRT2 (0.42) | SIRT2 | |
| SCHEMBL8733702 | 0.75 | TSHR (0.48) | ALDH1A1TSHRSLC22A6SLC22A8GPR84 | |
| SCHEMBL8736846 | 0.75 | TSHR (0.53) | OXER1AKR1B1ALDH1A1TSHRSLC22A6 | |
| SCHEMBL23533471 | 0.75 | TSHR (0.44) | OXER1ALDH1A1TSHRSLC22A6SLC22A8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524485-B2 | Skin lightening agents, compositions and methods | UNILEVER HOME & PERSONAL CARE, USA, DIVISION OF CONOPCO, INC. (US) | 2009-04-28 | — | — | US | disclosed |
| US-6875425-B2 | Skin lightening agents, compositions and methods | UNILEVER HOME & PERSONAL CARE USA (US) | 2005-04-05 | — | — | US | disclosed |
| US-5726345-A | Process for perfuming textiles | FIRMENICH S.A. (CH) | 1998-03-10 | — | — | US | disclosed |
| US-5649979-A | LAUNDERING IN PRESENCE OF ESTER COMPOUND WHICH RELEASES FRAGRANT ALCOHOL, ALDEHYDE OR KETONE | FIRMENICH S.A. (CH) | 1997-07-22 | — | — | US | disclosed |