Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4077939 | 0.93 | TRPV1 (0.79) | TRPV1OPRM1 | |
| SCHEMBL4079922 | 0.93 | TRPV1 (1.00) | TRPV1OPRM1 | |
| SCHEMBL4080172 | 0.87 | TRPV1 (0.89) | TRPV1OPRM1 | |
| SCHEMBL4075362 | 0.81 | TRPV1 (0.59) | TRPV1OPRM1 | |
| SCHEMBL4078155 | 0.80 | TRPV1 (0.77) | TRPV1OPRM1 | |
| SCHEMBL2525375 | 0.80 | TRPV1 (1.00) | TRPV1OPRM1 | |
| SCHEMBL2529530 | 0.79 | TRPV1 (1.00) | TRPV1OPRM1 | |
| SCHEMBL2525485 | 0.79 | TRPV1 (1.00) | TRPV1OPRM1 | |
| SCHEMBL2528530 | 0.78 | TRPV1 (1.00) | TRPV1 | |
| SCHEMBL4083977 | 0.78 | TRPV1 (0.76) | TRPV1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090286831-A1 | VR1 Receptor Ligands and u-Opioid Receptor Ligands for the Treatment of Pain | GRUENENTHAL GMBH (DE) | 2009-11-19 | — | — | US | claimed |
| EP-2083922-A1 | VR1 RECEPTOR LIGANDS AND µ OPIOID RECEPTOR LIGANDS FOR THE TREATMENT OF PAIN | Grünenthal GmbH (DE) | 2009-08-05 | — | — | EP | claimed |
| WO-2008046647-A1 | VR1 RECEPTOR LIGANDS AND µ OPIOID RECEPTOR LIGANDS FOR THE TREATMENT OF PAIN | Grünenthal GmbH (DE) | 2008-04-24 | — | — | WO | claimed |
| US-20090286831-A1 | VR1 Receptor Ligands and u-Opioid Receptor Ligands for the Treatment of Pain | GRUENENTHAL GMBH (DE) | 2009-11-19 | — | — | US | disclosed |
| EP-2083922-A1 | VR1 RECEPTOR LIGANDS AND µ OPIOID RECEPTOR LIGANDS FOR THE TREATMENT OF PAIN | Grünenthal GmbH (DE) | 2009-08-05 | — | — | EP | disclosed |
| WO-2008046647-A1 | VR1 RECEPTOR LIGANDS AND µ OPIOID RECEPTOR LIGANDS FOR THE TREATMENT OF PAIN | Grünenthal GmbH (DE) | 2008-04-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286831-A1 | VR1 Receptor Ligands and u-Opioid Receptor Ligands for the Treatment of Pain | OPRM1, OPRL1, OPRD1 | TRPV1 10/4885OPRM1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.