Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 7/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 7/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.34 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4075403 | 0.93 | NR1H3 (0.39) | NR1H2NR1H3CHRM2CHRM1CHRM3 | |
| SCHEMBL2277430 | 0.87 | NR1H2 (0.44) | NR1H2CHRM2CHRM1CHRM3USP2 | |
| SCHEMBL13733406 | 0.80 | TSHR (0.46) | NR1H2CHRM2CHRM1CHRM3SMN1; SMN2 | |
| SCHEMBL7531758 | 0.78 | NR1H3 (0.41) | NR1H2NR1H3CHRM2CHRM1CHRM3 | |
| SCHEMBL13733410 | 0.77 | TSHR (0.39) | NR1H2CHRM2CHRM1CHRM3SMN1; SMN2 | |
| SCHEMBL2030521 | 0.74 | HSD17B10 (0.41) | CHRM2CHRM1CHRM3USP2SMN1; SMN2 | |
| SCHEMBL3694111 | 0.74 | HSD17B10 (0.41) | CHRM2CHRM1CHRM3USP2SMN1; SMN2 | |
| SCHEMBL13932860 | 0.74 | NR1H2 (0.45) | NR1H2NR1H3CHRM2CHRM1CHRM3 | |
| SCHEMBL17980096 | 0.74 | HSD17B10 (0.41) | CHRM2CHRM1CHRM3USP2SMN1; SMN2 | |
| SCHEMBL4072044 | 0.74 | PIK3CD (0.35) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009038411-A2 | BETA-SECRETASE INHIBITING COMPOUNDS HAVING OXO-DIHYDRO-PYRAZOLE MOIETY | LG LIFE SCIENCES, LTD. (KR) | 2009-03-26 | — | — | WO | disclosed |