Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 4/20 | 0.35 |
| ▸ | BRS3 | P32247 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4075403 | 0.84 | NR1H3 (0.39) | SMN1; SMN2 | |
| SCHEMBL13733000 | 0.76 | SMN1; SMN2 (0.41) | SMN1; SMN2 | |
| SCHEMBL7443702 | 0.68 | KMT2A (0.33) | — | |
| SCHEMBL1003633 | 0.68 | PIK3CD (0.70) | PIK3CD | |
| SCHEMBL3951781 | 0.68 | PIK3CD (0.70) | PIK3CD | |
| SCHEMBL3952619 | 0.68 | PIK3CD (0.70) | PIK3CD | |
| SCHEMBL7489016 | 0.68 | KMT2A (0.33) | — | |
| SCHEMBL1914601 | 0.68 | KMT2A (0.33) | — | |
| SCHEMBL25895403 | 0.68 | — | — | |
| SCHEMBL25323532 | 0.67 | ALDH1A1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009038411-A2 | BETA-SECRETASE INHIBITING COMPOUNDS HAVING OXO-DIHYDRO-PYRAZOLE MOIETY | LG LIFE SCIENCES, LTD. (KR) | 2009-03-26 | — | — | WO | disclosed |