Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H3 | Q13133 | 7/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 7/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4075398 | 0.93 | NR1H2 (0.41) | NR1H3NR1H2CCR2CHRM2CHRM1 | |
| SCHEMBL4072044 | 0.84 | PIK3CD (0.35) | SMN1; SMN2 | |
| SCHEMBL2277430 | 0.84 | NR1H2 (0.44) | NR1H2HSD17B10CHRM2CHRM1CHRM3 | |
| SCHEMBL13733410 | 0.82 | TSHR (0.39) | NR1H2HSD17B10CHRM2CHRM1CHRM3 | |
| SCHEMBL13733406 | 0.77 | TSHR (0.46) | NR1H2HSD17B10CHRM2CHRM1CHRM3 | |
| SCHEMBL7531758 | 0.74 | NR1H3 (0.41) | NR1H3NR1H2HSD17B10CCR2CHRM2 | |
| SCHEMBL22342643 | 0.73 | NR1H2 (0.42) | NR1H2SMN1; SMN2GPR119 | |
| SCHEMBL1943071 | 0.73 | NR1H2 (0.42) | NR1H2SMN1; SMN2GPR119 | |
| SCHEMBL5718903 | 0.73 | HSD17B10 (0.39) | NR1H2HSD17B10SMN1; SMN2 | |
| SCHEMBL17980096 | 0.71 | HSD17B10 (0.41) | HSD17B10CHRM2CHRM1CHRM3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009038411-A2 | BETA-SECRETASE INHIBITING COMPOUNDS HAVING OXO-DIHYDRO-PYRAZOLE MOIETY | LG LIFE SCIENCES, LTD. (KR) | 2009-03-26 | — | — | WO | disclosed |