SCHEMBL4075696

SCHEMBL4075696

O=C(O)c1ccc(C(=O)c2cccc(C(=O)O)c2C(=O)OC(=O)c2c(C(=O)O)cccc2C(=O)c2ccc(C(=O)O)c(C(=O)O)c2)cc1C(=O)O

nearest known ligand 0.65

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 2/20 0.65
CDC25A P30304 1/20 0.65
HSD17B10 Q99714 1/20 0.65
POLB P06746 4/20 0.50
TDP1 Q9NUW8 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
KDM4E B2RXH2 1/20 0.50
ALDH1A1 P00352 3/20 0.46
AKR1C3 P42330 3/20 0.44
ATM Q13315 1/20 0.44
LMNA P02545 1/20 0.43
NR4A1 P22736 1/20 0.42
ALOX15 P16050 1/20 0.39
HPSE Q9Y251 2/20 0.39
MYC P01106 1/20 0.38
PTPN1 P18031 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL64990 0.87 CDC25B (0.79) CDC25BCDC25AHSD17B10POLBTDP1
SCHEMBL1271123 0.83 AKR1C3 (0.60) CDC25BCDC25AHSD17B10POLBTDP1
SCHEMBL4017455 0.82 CDC25B (0.53) CDC25BCDC25AHSD17B10POLBALDH1A1
SCHEMBL11452607 0.81 CDC25B (0.75) CDC25BCDC25AHSD17B10POLBTDP1
SCHEMBL4842453 0.81 CDC25A (0.59) CDC25BCDC25AHSD17B10POLBTDP1
SCHEMBL7890067 0.80 KDM4E (0.49) CDC25BCDC25AHSD17B10POLBTDP1
SCHEMBL109745 0.80 CDC25B (0.46) CDC25BCDC25AHSD17B10POLBALDH1A1
SCHEMBL168534 0.80 POLB (0.65) CDC25BCDC25AHSD17B10POLBTDP1
SCHEMBL2058645 0.79 CDC25B (1.00) CDC25BCDC25AHSD17B10POLBTDP1
SCHEMBL3074652 0.79 CDC25B (1.00) CDC25BCDC25AHSD17B10POLBTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090101280-A1 METHOD OF PRODUCING FLEXIBLE SINGLE-SIDED POLYIMIDE COPPER-CLAD LAMINATE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-04-23 US disclosed