Procainamide

Procainamide

SCHEMBL40758

CCN(CC)CCNC(=O)c1ccc(N)cc1.Cl

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9A

The experimentally established mechanism targets of Procainamide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SCN1A known ✓ P35498 1/20 0.60
SCN2A known ✓ Q99250 1/20 0.60
SCN3A known ✓ Q9NY46 1/20 0.60
BLM P54132 3/20 1.00
LMNA P02545 2/20 1.00
PMP22 Q01453 1/20 1.00
ALDH1A1 P00352 3/20 0.97
TSHR P16473 2/20 0.97
SLC22A2 O15244 1/20 0.97
SLC22A1 O15245 1/20 0.97
ACHE P22303 1/20 0.97
MAPK1 P28482 1/20 0.97
CYP2C19 P33261 1/20 0.97
POLB P06746 2/20 0.68
CYP3A4 P08684 1/20 0.68
THRB P10828 1/20 0.68
ATM Q13315 1/20 0.68
SMN1; SMN2 Q16637 1/20 0.68
NFKB1 P19838 1/20 0.65
KCNH2 Q12809 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Procainamide SCHEMBL9614531 1.00 BLM (1.00) BLMLMNAPMP22ALDH1A1TSHR
Procainamide SCHEMBL10717171 0.98 BLM (0.97) BLMLMNAPMP22ALDH1A1TSHR
Procainamide SCHEMBL9592794 0.98 BLM (0.97) BLMLMNAPMP22ALDH1A1TSHR
Procainamide SCHEMBL5443536 0.98 BLM (0.97) BLMLMNAPMP22ALDH1A1TSHR
Procainamide SCHEMBL9437783 0.98 BLM (0.97) BLMLMNAPMP22ALDH1A1TSHR
Procainamide SCHEMBL23270847 0.98 BLM (0.97) BLMLMNAPMP22ALDH1A1TSHR
Procainamide SCHEMBL9618624 0.98 BLM (0.97) BLMLMNAPMP22ALDH1A1TSHR
Procainamide SCHEMBL15914 0.98 ALDH1A1 (1.00) BLMLMNAPMP22ALDH1A1TSHR
Procainamide SCHEMBL28944214 0.97 ALDH1A1 (0.97) BLMLMNAPMP22ALDH1A1TSHR
Procainamide SCHEMBL341750 0.95 ALDH1A1 (0.94) BLMLMNAPMP22ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5042 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4729064-A1 DE-DIFFERENTIATED FIBROBLAST-CONDITIONED MEDIA FOR TREATING OR PREVENTING DISC DEGENERATION FibroBiologics, Inc. (US) 2026-04-22 EP claimed
EP-3787647-B1 DE-DIFFERENTIATED FIBROBLAST-CONDITIONED MEDIA FOR TREATING OR PREVENTING DISC DEGENERATION FIBROBIOLOGICS INC (US) 2026-04-15 EP claimed
EP-4691556-A2 HUMANIZED ANTI-ACTH ANTIBODIES AND USE THEREOF H. Lundbeck A/S (DK) 2026-02-11 EP claimed
US-20250135164-A1 Controlled Release Of A Hydrophilic Agent From A Coated Surface BIOCOAT, INCORPORATED 2025-05-01 US claimed
CN-119546605-A Protein degradation agent 苏州开拓药业股份有限公司 2025-02-28 CN claimed
US-12214146-B2 Controlled release of a hydrophilic agent from a coated surface BIOCOAT, INCORPORATED (US) 2025-02-04 US claimed
WO-2024027694-A9 PROTEIN DEGRADATION AGENT 苏州开拓药业股份有限公司 2025-01-02 WO claimed
US-20240390364-A1 Novel Pyridine Compositions and their use in methods for preventing or treating diseases, disorders and conditions REID CHRISTOPHER BRIAN (US) 2024-11-28 US claimed
US-20240350643-A1 PROTEIN DEGRADATION AGENT SUZHOU KINTOR PHARMACEUTICALS, INC. (CN) 2024-10-24 US claimed
US-20240282425-A1 AUTHENTICATION METHODS AND SYSTEMS FOR DISPENSED PRESCRIPTIONS LOW GORDON KEITH (US) 2024-08-22 US claimed
EP-0248447-B1 SUSTAINED RELEASE FORMULATIONS WARNER-LAMBERT COMPANY (US) 1990-04-18 EP claimed
US-4851233-A TABLET BINDER MIXTURE OF PROCAINAMIDE HYDROCHLORIDE OR SODIUM MECLOFENAMATE AND HYDROXY ETHYL CELLULOSE FOR MATRIX DISINTEGRATION WARNER-LAMBERT COMPANY (US) 1989-07-25 US claimed
US-4816264-A PROCAINAMIDE HYDROCHLORIDE, DRUG DELIVERY WARNER-LAMBERT COMPANY (US) 1989-03-28 US claimed
US-4756911-A Tablet core of procainamide hydrochloride and hydrocolloid gelling agents, binders, hydrophobic and hydrophilic polymers E. R. SQUIBB & SONS, INC. (US) 1988-07-12 US claimed
EP-0248447-A2 Sustained release formulations WARNER-LAMBERT COMPANY (US) 1987-12-09 EP claimed
US-4610870-A PROCAINAMIDE HYDROCHLORIDE E. R. SQUIBB & SONS, INC. (US) 1986-09-09 US claimed
EP-0189861-A2 Percutaneous absorption accelerator for ionic water-soluble medicine SHOWA DENKO KABUSHIKI KAISHA (JP) 1986-08-06 EP claimed
US-4252786-A POLYVINYLPYRROLIDONE WITH CARBOXYVINYL HYDROPHILIC POLYMER, INSOLUBLE BUT RUPTURABLE FILM E. R. SQUIBB & SONS, INC. (US) 1981-02-24 US claimed
US-4008719-A Osmotic system having laminar arrangement for programming delivery of active agent ALZA CORPORATION (US) 1977-02-22 US claimed
US-3965255-A DRUG ENCAPSULATED IN OR COATED WITH A SOLVENT MEMBRANE E. E. ELJIM ECOLOGY LTD. (IL) 1976-06-22 US claimed